| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4388468 | A | Inhibition of recombinant C-terminal 10His-tagged human KLK14 (Gln19 to Met248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 2. | ALA4388469 | B | Inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected Sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate measured at 30 secs interval for 5 mins by fluorescence intensity assay | Homo sapiens | 27 | ALA4387717 | cell-based format | Scientific Literature | |
| 3. | ALA4388470 | A | Inhibition of recombinant bovine enterokinase activated N-terminal His-tagged recombinant human KLK1 (19 to 262 residues) expressed in baculovirus infected Sf9 insect cells using 3',6'-bis(prolylphenylalanylarginylamino)3H-spiro(2-benzofuran-1,9'-xanthen)-3-one;TFA as substrate measured at 30 secs interval for 5 mins by fluorescence intensity assay | Homo sapiens | 27 | ALA4387717 | cell-based format | Scientific Literature | |
| 4. | ALA4388472 | A | Inhibition of recombinant C-terminal 6-His tagged human KLKB1 (Gly20 to Ala638 residues) expressed in mouse NS0 cells using P-F-R-AMC as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 5. | ALA4388473 | A | Inhibition of recombinant C-terminal 10His-tagged human KLK7 (Glu23 to His252 residues) expressed in mouse NS0 cells using 5-FAM-E-A-L-Y-L-V-S-G-C as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 6. | ALA4388474 | A | Inhibition of recombinant C-terminal 10-His tagged human KLK8 (Gln29 to Gly260 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 7. | ALA4388475 | A | Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insect cells using Mca-RPKPVE-Nval-WRK(Dnp)-NH2 as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 8. | ALA4388476 | A | Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli using Boc-QAR-AMC as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | assay format | Scientific Literature | |
| 9. | ALA4388477 | A | Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | single protein format | Scientific Literature | |
| 10. | ALA4388478 | A | Inhibition of recombinant C-terminal 10His-tagged human thrombin (Met1 to Glu622 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 11. | ALA4388479 | A | Inhibition of recombinant C-terminal 10His-tagged human urokinase (Met1 to Leu431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 40 mins by fluorescence intensity assay | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 12. | ALA4388480 | U | Selectivity index, ratio of compound effect for inhibition of recombinant C-terminal 6-His tagged human KLKB1 (Gly20 to Ala638 residues) expressed in mouse NS0 cells to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 13. | ALA4388481 | U | Selectivity index, ratio of compound effect for inhibition of recombinant C-terminal 10-His tagged human KLK7 (Glu23 to His252 residues) expressed in mouse NS0 cells to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 14. | ALA4388482 | U | Selectivity index, ratio of compound effect for inhibition of recombinant C-terminal 10-His tagged human KLK14 (Gln19 to Met248 residues) expressed in mouse NS0 cells to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 15. | ALA4388483 | U | Selectivity index, ratio of compound effect for inhibition of recombinant C-terminal 10-His tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected insect Sf9 cells to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 16. | ALA4388484 | U | Selectivity index, ratio of compound effect for inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 17. | ALA4388485 | U | Selectivity index, ratio of compound effect for inhibition of human neutrophil elastase to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 18. | ALA4388486 | U | Selectivity index, ratio of compound effect for inhibition of recombinant C-terminal 10-His tagged human thrombin (Met1 to Glu622 residues) expressed in mouse NS0 cells to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 19. | ALA4388487 | U | Selectivity index, ratio of compound effect for inhibition of recombinant C-terminal 10-His tagged human urokinase (Met1 to Leu431 residues) expressed in mouse NS0 cells to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature | |
| 20. | ALA4388488 | U | Selectivity index, ratio of compound effect for inhibition of recombinant C-terminal 10-His tagged human KLK8 (Gln29 to Gly260 residues) expressed in mouse NS0 cells to compound effect for inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected insect Sf9 cells | Homo sapiens | 1 | ALA4387717 | cell-based format | Scientific Literature |
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