# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4329743 | B | Inhibition of human PMN leukocytes MPO chlorination activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured for 15 mins in presence of NaCl by aminophenyl fluorescein based assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
2. | ALA4329744 | B | Inhibition of human PMN leukocytes MPO peroxidation activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured for 15 mins by amplex red reagent based assay | Homo sapiens | 25 | assay format | Scientific Literature | ||
3. | ALA4329746 | P | Half life in pH 1 solution | 2 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA4329747 | A | AUC in mouse at 3 mg/kg, po after 8 hrs | Mus musculus | 3 | organism-based format | Scientific Literature | ||
5. | ALA4329748 | A | Inhibition of recombinant human N-terminal His-tagged MGMT (1 to 207 residues) expressed in Escherichia coli using O-6-benzylguanine as substrate after 30 mins by LC-MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
6. | ALA4703099 | B | Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
7. | ALA4703100 | B | Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
8. | ALA4703101 | A | Inhibition of human MGMT using 06-benzylguanine as substrate incubated for 30 mins by LC/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
9. | ALA4703102 | P | Stability of compound at pH 1 assessed as half life | 4 | small-molecule physicochemical format | Scientific Literature |