| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4375055 | ADME | Antagonist activity at beta1 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes assessed as inhibition of isoproterenol-induced cAMP production preincubated for 15 mins followed by isoproterenol addition and measured after 30 mins by TR-FRET assay | Homo sapiens | 24 | ALA4373696 | cell-based format | Scientific Literature | |
| 2. | ALA4375056 | Functional | Antagonist activity at beta2 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes assessed as inhibition of isoproterenol-induced cAMP production preincubated for 15 mins followed by isoproterenol addition and measured after 30 mins by TR-FRET assay | Homo sapiens | 30 | ALA4373696 | cell-based format | Scientific Literature | |
| 3. | ALA4375057 | Binding | Selectivity ratio of IC50 for antagonist activity at beta1 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes to IC50 for antagonist activity at beta2 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes | Homo sapiens | 24 | ALA4373696 | cell-based format | Scientific Literature | |
| 4. | ALA4375058 | Functional | Antagonist activity at beta2 adrenergic receptor (unknown origin) expressed in HEK293 cell assessed as inhibition of isoproterenol-induced cAMP production preincubated for 15 mins followed by isoproterenol addition and measured after 15 mins | Homo sapiens | 17 | ALA4373696 | cell-based format | Scientific Literature | |
| 5. | ALA4375059 | ADME | Displacement of [3H]DHA from beta1 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes measured after 90 mins by scintillation counting analysis | Homo sapiens | 17 | ALA4373696 | cell-based format | Scientific Literature | |
| 6. | ALA4375060 | Binding | Displacement of [3H]DHA from beta2 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes measured after 90 mins by scintillation counting analysis | Homo sapiens | 18 | ALA4373696 | cell-based format | Scientific Literature | |
| 7. | ALA4375061 | Unassigned | Selectivity ratio of Ki for displacement of [3H]DHA from beta1 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes to displacement of [3H]DHA from beta2 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes | Homo sapiens | 17 | ALA4373696 | cell-based format | Scientific Literature |
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