| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4322320 | B | Inhibition of biotinylated Bim peptide (81 to 106 residues) binding to His-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) cells preincubated for 1 hr followed by biotinylated Bim peptide addition measured after 2 hrs by ELISA | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 2. | ALA4322321 | B | Inhibition of biotinylated Bim peptide (81 to 106 residues) binding to His-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) cells preincubated for 1 hr followed by biotinylated Bim peptide addition measured after 2 hrs by ELISA | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA4322322 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 10 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA4322324 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 10 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 5. | ALA4322326 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells at 10 uM after 12 hrs by Western blot analysis relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA4322327 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells at 10 uM after 12 hrs by Western blot analysis relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA4322371 | F | Cytotoxicity against human H23 cells incubated for 24 hrs by CCK8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4322373 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as Mcl-1 level at 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4322374 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as reduction in Bcl-2 level at 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA5234940 | B | Inhibition of Bcl-2/Mcl-1 in human MCF7 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5234941 | B | Inhibition of Bcl-2 (unknown origin) by ELISA analysis | Homo sapiens | 1 | single protein format | Scientific Literature |
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