# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4313574 | Binding | Inhibition of porcine brain tubulin polymerization assessed as decrease in fluorescence intensity measured every 60 sec for 90 mins in presence of GTP by DAPI staining based fluorescence assay | Sus scrofa | 4 | ALA4311964 | assay format | Scientific Literature | |
2. | ALA4313575 | Functional | Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 20 | ALA4311964 | cell-based format | Scientific Literature | |
3. | ALA4313576 | Functional | Antiproliferative activity against human HL60 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 20 | ALA4311964 | cell-based format | Scientific Literature | |
4. | ALA4313577 | Functional | Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 20 | ALA4311964 | cell-based format | Scientific Literature | |
5. | ALA4313578 | Binding | Inhibition of tubulin beta polymerization in human HepG2 cells at IC50 using TMB substrate preincubated for 2 hrs followed by substrate addition measured after 15 to 20 mins in presence of GTP by ELISA relative to control | Homo sapiens | 4 | ALA4311964 | cell-based format | Scientific Literature | |
6. | ALA4313579 | Binding | Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assay | Bos taurus | 3 | ALA4311964 | assay format | Scientific Literature |