# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4480875 | B | Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISA | Homo sapiens | 42 | assay format | Scientific Literature | ||
2. | ALA4480878 | B | Binding affinity to Rad51 in human BxPC3 cells assessed as reduction in protein-mediated homologous recombination at 20 uM measured after 16 hrs by reporter gene based PCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4480880 | F | Effect on homologous recombination in human Capan1 cells at 10 to 20 uM measured after 16 hrs by reporter gene based PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4480883 | F | Synergistic cytotoxicity against human BxPC3 cells assessed as reduction in cell viability at 20 uM measured after 72 hrs in presence of PARP inhibitor olaparib by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4480885 | F | Synergistic cytotoxicity against human Capan1 cells assessed as reduction in cell viability at 20 uM measured after 72 hrs in presence of PARP inhibitor olaparib by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4480886 | F | Synergistic cytotoxicity against human BxPC3 cells assessed as reduction in cell viability measured after 72 hrs in presence of PARP inhibitor olaparib by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4480887 | F | Synergistic cytotoxicity against human BxPC3 cells assessed as reduction in cell viability at 20 uM measured after 144 hrs in presence of PARP inhibitor olaparib by CellTox green dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4480888 | F | Synergistic cytotoxicity against human BxPC3 cells assessed as combination index at 20 uM measured after 144 hrs in presence of PARP inhibitor olaparib by CellTox green dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4480889 | F | Induction of DNA damage in human BxPC3 cells assessed as increase in gammaH2AX phosphorylation level at 20 uM measured after 144 hrs in presence of PARP inhibitor olaparib by Western blotting analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4480890 | F | Induction of DNA damage in human BxPC3 cells assessed as increase in gammaH2AX phosphorylation level at 20 uM measured after 144 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4480891 | F | Induction of apoptosis in human BxPC3 cells assessed as increase in PUMA level at 20 uM measured after 144 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4480892 | F | Induction of apoptosis in human BxPC3 cells assessed as increase in BAX level at 20 uM measured after 144 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4480893 | F | Induction of apoptosis in human BxPC3 cells assessed as caspase-3 activation at 20 uM measured after 144 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |