#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4384934	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis	Rattus norvegicus	2		cell-based format	Scientific Literature
2.	ALA4384935	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 10 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis	Rattus norvegicus	3		cell-based format	Scientific Literature
3.	ALA4384936	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 10 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis	Rattus norvegicus	3		cell-based format	Scientific Literature
4.	ALA4384937	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis	Rattus norvegicus	2		cell-based format	Scientific Literature
5.	ALA4384945	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 20 uM preincubated for 1 hr followed by induction of hypoxia measured after 3 hrs by NADP reduction based colorimetric analysis	Rattus norvegicus	1		cell-based format	Scientific Literature
6.	ALA4384946	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH levels by measuring NADH levels at 20 uM preincubated for 1 hr followed by induction of hypoxia measured after 3 hrs by colorimetric analysis	Rattus norvegicus	1		cell-based format	Scientific Literature
7.	ALA4384947	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 5 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis	Rattus norvegicus	1		cell-based format	Scientific Literature
8.	ALA4384948	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 5 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis	Rattus norvegicus	1		cell-based format	Scientific Literature
9.	ALA4384949	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 30 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis	Rattus norvegicus	1		cell-based format	Scientific Literature
10.	ALA4384950	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 30 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis	Rattus norvegicus	1		cell-based format	Scientific Literature
11.	ALA4384951	F	Reduction in hypoxia-induced TLR4 mRNA expression in Sprague-Dawley rat cardiomyocytes at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by RT-qPCR analysis relative to untreated control	Rattus norvegicus	2		cell-based format	Scientific Literature
12.	ALA4384952	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced IL-1beta mRNA expression at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by RT-qPCR analysis	Rattus norvegicus	2		cell-based format	Scientific Literature
13.	ALA4384953	F	Reduction in hypoxia-induced TLR4 protein expression in Sprague-Dawley rat cardiomyocytes at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by Western blot analysis relative to untreated control	Rattus norvegicus	1		cell-based format	Scientific Literature
14.	ALA4384954	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced TRAM protein expression at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by Western blot analysis relative to untreated control	Rattus norvegicus	1		cell-based format	Scientific Literature
15.	ALA4384955	B	Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced IRF3 protein expression at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by Western blot analysis relative to untreated control	Rattus norvegicus	1		cell-based format	Scientific Literature
16.	ALA4384957	B	Inhibition of TLR4 in hypoxia-induced Sprague-Dawley rat cardiomyocytes assessed as increase in IkappaB-alpha protein expression at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by Western blot analysis relative to untreated control	Rattus norvegicus	1		assay format	Scientific Literature
17.	ALA4384961	A	Cytotoxicity against Sprague-Dawley rat cardiomyocytes assessed as reduction in cell viability at 50 uM	Rattus norvegicus	1		cell-based format	Scientific Literature
18.	ALA4384962	B	Binding affinity to TLR4 in Sprague-Dawley rat cardiomyocytes at 20 uM after 2 hrs by MS/MS-based pull down assay	Rattus norvegicus	1		cell-based format	Scientific Literature
19.	ALA4384963	F	Cardioprotective activity in C57BL mouse model of left anterior descending coronary artery ligation-induced myocardial ischemia assessed as reduction in creatine kinase levels at 0.3 mg/kg, iv pretreated for 1 hr followed by left anterior descending coronary artery ligation	Mus musculus	1		organism-based format	Scientific Literature
20.	ALA4384964	F	Cardioprotective activity in C57BL mouse model of left anterior descending coronary artery ligation-induced myocardial ischemia assessed as reduction in LDH kinase levels at 0.3 mg/kg, iv pretreated for 1 hr followed by left anterior descending coronary artery ligation	Mus musculus	1		organism-based format	Scientific Literature