# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4322424 | B | Anti-prion activity against [PSI+] protein in Saccharomyces cerevisiae STRg6 measured after 24 hrs by fluorimetry analysis | Saccharomyces cerevisiae | 7 | ALA4321801 | assay format | Scientific Literature | |
2. | ALA4322425 | B | Anti-prion activity against [URE3] protein in Saccharomyces cerevisiae SB34 at 100 uM measured after 24 hrs by fluorimetry analysis | Saccharomyces cerevisiae | 7 | ALA4321801 | assay format | Scientific Literature | |
3. | ALA5255021 | B | Binding affinity to human alpha-syn expressed in Escherichia coli BL21 (DE3) cells assessed as protein-compound complex formation at 100 uM incubated for 3 hrs by ESI-MS spectrum analysis | Homo sapiens | 16 | ALA5252574 | cell-based format | Scientific Literature | |
4. | ALA5255022 | B | Inhibition of human alpha-syn expressed in Escherichia coli BL21 (DE3) cells aggregation at 80 uM incubated at compound:protein ratio of 1:1 for 36 hrs by ThT dye based fluorescence assay relative to control | Homo sapiens | 6 | ALA5252574 | cell-based format | Scientific Literature | |
5. | ALA5255023 | B | Inhibition of human alpha-syn expressed in Escherichia coli BL21 (DE3) cells aggregation at 400 uM incubated at compound:protein ratio of 5:1 for 36 hrs by ThT dye based fluorescence assay relative to control | Homo sapiens | 7 | ALA5252574 | cell-based format | Scientific Literature | |
6. | ALA5255025 | F | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 25923 incubated for 18 hrs by microdilution method | Staphylococcus aureus | 3 | ALA5252574 | organism-based format | Scientific Literature | |
7. | ALA5255026 | F | Antibacterial activity against methicillin- resistant Staphylococcus aureus ATCC 43300 incubated for 18 hrs by microdilution method | Staphylococcus aureus | 3 | ALA5252574 | organism-based format | Scientific Literature | |
8. | ALA5255027 | F | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated for 18 hrs by microdilution method | Pseudomonas aeruginosa | 3 | ALA5252574 | organism-based format | Scientific Literature |