# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4372487 | Binding | Displacement of biotin-labeled geldanamycin from His-tagged HSP90alpha NTD (unknown origin) preincubated for 2 hrs followed by biotin-labeled geldanamycin addition and measured after 1 hr by AlphaScreen assay | Homo sapiens | 33 | ALA4371046 | single protein format | Scientific Literature | |
2. | ALA4372488 | Functional | Growth inhibition of human SK-BR-3 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 29 | ALA4371046 | cell-based format | Scientific Literature | |
3. | ALA4372489 | Physicochemical | 1-octanol/aqueous buffer partition coefficient, log D of the compound at pH 7.4 by HPLC method | 10 | ALA4371046 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4372491 | Physicochemical | Solubility of the compound in pH 7.4 solution by chromatography method | 6 | ALA4371046 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4372492 | ADME | AUC (0 to 6 hrs) in Balb/cA mouse at 50 mg/kg, po by LC-MS/MS analysis | Mus musculus | 6 | ALA4371046 | organism-based format | Scientific Literature |