# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4428279 | Binding | Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS1 substrate | Human immunodeficiency virus 1 | 66 | ALA4428027 | single protein format | Scientific Literature | |
2. | ALA4428280 | Binding | Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrate | Human immunodeficiency virus 1 | 65 | ALA4428027 | single protein format | Scientific Literature | |
3. | ALA4428281 | Binding | Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3 substrate | Human immunodeficiency virus 1 | 65 | ALA4428027 | single protein format | Scientific Literature | |
4. | ALA4428282 | Binding | Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragment | Human immunodeficiency virus 1 | 65 | ALA4428027 | single protein format | Scientific Literature | |
5. | ALA4428283 | Binding | Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation spectrometry | Human immunodeficiency virus 1 | 66 | ALA4428027 | single protein format | Scientific Literature | |
6. | ALA4428284 | Binding | Inhibition of HIV1 polymerase activity of reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP up to 25 uM incubated for 20 mins by liquid scintillation spectrometry | Human immunodeficiency virus 1 | 40 | ALA4428027 | single protein format | Scientific Literature | |
7. | ALA4428285 | Toxicity | Toxicity against human HeLa P4/R5 cells | Homo sapiens | 66 | ALA4428027 | cell-based format | Scientific Literature |