| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4393185 | Binding | Inhibition of MMP2 (unknown origin) pre-incubated for 5 mins before Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate addition and measured over 30 mins by fluorometric assay | Homo sapiens | 8 | ALA4392837 | single protein format | Scientific Literature | |
| 2. | ALA4393186 | Binding | Inhibition of MMP9 (unknown origin) pre-incubated for 5 mins before Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate addition and measured over 30 mins by fluorometric assay | Homo sapiens | 8 | ALA4392837 | single protein format | Scientific Literature | |
| 3. | ALA4393187 | Binding | Selectivity index, ratio of IC50 for MMP9 (unknown origin) to IC50 for MMP2 (unknown origin) | Homo sapiens | 8 | ALA4392837 | assay format | Scientific Literature | |
| 4. | ALA4393188 | Functional | Cytotoxicity in human human MCF7 cells assessed as reduction in cell viability at 0.001 to 5 uM incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA4392837 | cell-based format | Scientific Literature | |
| 5. | ALA4393189 | Functional | Cytotoxicity in human human MCF7 cells assessed as effect on cell integrity at 0.001 to 5 uM incubated for 24 hrs by trypan blue exclusion assay | Homo sapiens | 3 | ALA4392837 | cell-based format | Scientific Literature | |
| 6. | ALA4393190 | Functional | Cytotoxicity in human human HCT116 cells assessed as reduction in cell viability at 0.001 to 5 uM incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA4392837 | cell-based format | Scientific Literature | |
| 7. | ALA4393191 | Functional | Cytotoxicity in human human HCT116 cells assessed as effect in cell integrity at 0.001 to 5 uM incubated for 24 hrs by trypan blue exclusion assay | Homo sapiens | 3 | ALA4392837 | cell-based format | Scientific Literature | |
| 8. | ALA4393192 | Functional | Cytotoxicity in human human A375M6 cells assessed as reduction in cell viability at 50 nM to 5 uM incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA4392837 | cell-based format | Scientific Literature | |
| 9. | ALA4393193 | Functional | Cytotoxicity in human human A375M6 cells assessed as effect on cell integrity at 0.001 to 5 uM incubated for 24 hrs by trypan blue exclusion assay | Homo sapiens | 3 | ALA4392837 | cell-based format | Scientific Literature | |
| 10. | ALA4393194 | Functional | Inhibition of cell migration of human A375M6 cells at 10 uM incubated for 6 hrs by Boyden chambers assay relative to Ilomastat | Homo sapiens | 3 | ALA4392837 | assay format | Scientific Literature | |
| 11. | ALA4393195 | Functional | Inhibition of cell migration of human A375M6 cells at 1 uM incubated for 6 hrs by Boyden chambers assay relative to Ilomastat | Homo sapiens | 3 | ALA4392837 | assay format | Scientific Literature |
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