| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4433550 | Binding | Agonist activity at GST-tagged FXR-LBD (unknown origin) assessed as biotin-labeled SRC-1 recruitment at 5 uM after 30 mins by Alpha Screen assay relative to CDCA | Homo sapiens | 23 | ALA4433207 | single protein format | Scientific Literature | |
| 2. | ALA4433551 | Binding | Agonist activity at GST-tagged FXR-LBD (unknown origin) assessed as biotin-labeled SRC-1 recruitment at 5 uM after 30 mins by Alpha Screen assay relative to 6-ECDCA | Homo sapiens | 23 | ALA4433207 | single protein format | Scientific Literature | |
| 3. | ALA4433552 | Binding | Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase reporter gene assay | Homo sapiens | 24 | ALA4433207 | cell-based format | Scientific Literature | |
| 4. | ALA4433561 | Functional | Agonist activity at human GPBAR1 expressed in HEK293T cells at 10 uM after 18 hrs by cAMP response element driven luciferase reporter gene assay | Homo sapiens | 21 | ALA4433207 | cell-based format | Scientific Literature |
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