| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4479462 | B | Inhibition of EZH2 histone methyltransferase activity of EZH2/EED/SUZ12 protein complex (unknown origin) using histone H3 peptide as substrate (21 to 44 residues) in presence of [3H]-S-adenosylmethionine after 2 hrs by scintillation proximity assay | Homo sapiens | 54 | single protein format | Scientific Literature | ||
| 2. | ALA4479463 | B | Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as substrate (21 to 44 residues) in presence of [3H]-S-adenosylmethionine after 2 hrs by scintillation proximity assay | Homo sapiens | 54 | single protein format | Scientific Literature | ||
| 3. | ALA5111868 | B | Binding affinity to recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant incubated for 90 seconds by surface plasmon resonance assay | Homo sapiens | 17 | assay format | Scientific Literature | ||
| 4. | ALA5111869 | B | Binding affinity to recombinant PRC2 complex (unknown origin) assessed as association rate constant incubated for 90 seconds by surface plasmon resonance assay | Homo sapiens | 17 | assay format | Scientific Literature | ||
| 5. | ALA5111870 | B | Binding affinity to recombinant PRC2 complex (unknown origin) incubated for 90 seconds by surface plasmon resonance assay | Homo sapiens | 17 | assay format | Scientific Literature | ||
| 6. | ALA5111871 | B | Inhibition of EZH2 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 7. | ALA5111872 | F | Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 8. | ALA5111873 | F | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 9. | ALA5111874 | F | Antiproliferative activity against human SU-DHL-10 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 10. | ALA5111875 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 11. | ALA5111876 | F | Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 12. | ALA5111917 | F | Synergistic antiproliferative activity against human HL-60 cells assessed as combination index in presence of SAHA incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA5111918 | F | Synergistic antiproliferative activity against human MV4-11 cells assessed as combination index in presence of SAHA incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA5111919 | F | Synergistic antiproliferative activity against human SU-DHL-10 cells assessed as combination index in presence of SAHA incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA5111920 | F | Synergistic antiproliferative activity against human MDA-MB-231 cells assessed as combination index in presence of SAHA incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA5111921 | F | Synergistic antiproliferative activity against human HCT-116 cells assessed as combination index in presence of SAHA incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA5231258 | B | Inhibition of EZH2 methyltransferase activity (unknown origin) assessed `transfer of [3H]methyl group from SAM to substrate by biochemical assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 18. | ALA5231259 | B | Inhibition of EZH1 methyltransferase activity (unknown origin) assessed `transfer of [3H]methyl group from SAM to substrate by biochemical assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5238024 | B | Inhibition of EZH2 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!