| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4343050 | B | Inhibition of N-terminal TEV cleavage site-fused His6 tagged Leishmania major NMT (11 to 421 residues) expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Leishmania major | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA4343051 | A | Inhibition of N-terminal TEV cleavage site-fused His6 tagged human NMT1 (115 to 496 residues) expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA4343052 | T | Selectivity index, ratio of Ki for inhibition of N-terminal TEV cleavage site-fused His6 tagged human NMT1 (115 to 496 residues) to Ki for inhibition of N-terminal TEV cleavage site-fused His6 tagged Leishmania major NMT (11 to 421 residues) | 8 | assay format | Scientific Literature | |||
| 4. | ALA4343053 | B | Inhibition of Leishmania major NMT H398N/M420L/L421Q mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Leishmania major | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA4343054 | A | Inhibition of human NMT1 N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA4343055 | B | Inhibition of Leishmania major NMT H398N mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Leishmania major | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA4343056 | B | Inhibition of Leishmania major NMT M420L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Leishmania major | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA4343057 | B | Inhibition of Leishmania major NMT L421Q mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Leishmania major | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA4343058 | A | Inhibition of human NMT1 L495M mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA4343059 | A | Inhibition of human NMT1 Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins by CPM dye based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature |
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