# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4413528 | Functional | Induction of apoptosis in human MV4-11 cells assessed as late apoptotic cells at 20 nM after 48 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 5.03%) | Homo sapiens | 1 | ALA4411315 | cell-based format | Scientific Literature | |
2. | ALA4413533 | Functional | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 28 | ALA4411315 | cell-based format | Scientific Literature | |
3. | ALA4413534 | Functional | Antiproliferative activity against human Raji cells after 72 hrs by MTT assay | Homo sapiens | 28 | ALA4411315 | cell-based format | Scientific Literature | |
4. | ALA4413536 | Functional | Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay | Homo sapiens | 28 | ALA4411315 | cell-based format | Scientific Literature | |
5. | ALA4413539 | Binding | Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4411315 | single protein format | Scientific Literature | |
6. | ALA4413540 | Binding | Inhibition of recombinant full length human HDAC2 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4411315 | assay format | Scientific Literature | |
7. | ALA4413541 | Binding | Inhibition of recombinant full length HDAC3 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4411315 | single protein format | Scientific Literature | |
8. | ALA4413542 | Binding | Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4411315 | assay format | Scientific Literature | |
9. | ALA4413543 | Binding | Inhibition of recombinant full length HDAC6 (unknown origin) using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4411315 | single protein format | Scientific Literature | |
10. | ALA4413544 | Binding | Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 3 | ALA4411315 | cell-based format | Scientific Literature | |
11. | ALA4413545 | Binding | Inhibition of recombinant N-terminal FLAG-tagged human mTOR (1362 to end residues) using ULight-4E-BP1 (Thr37/46) peptide as substrate after 1 hr by fluorescence assay | Homo sapiens | 4 | ALA4411315 | single protein format | Scientific Literature | |
12. | ALA4413546 | Binding | Inhibition of recombinant full length human HDAC4 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 2 | ALA4411315 | cell-based format | Scientific Literature | |
13. | ALA4413547 | Binding | Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 2 | ALA4411315 | assay format | Scientific Literature | |
14. | ALA4413548 | Binding | Inhibition of recombinant full length N-terminal GST-tagged human HDAC7 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 2 | ALA4411315 | assay format | Scientific Literature | |
15. | ALA4413549 | Binding | Inhibition of recombinant full length C-terminal His-tagged human HDAC9 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 2 | ALA4411315 | assay format | Scientific Literature | |
16. | ALA4413550 | Binding | Inhibition of recombinant full length N-terminal GST-tagged human HDAC11 expressed in baculovirus expression system using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay | Homo sapiens | 2 | ALA4411315 | assay format | Scientific Literature | |
17. | ALA4413551 | Functional | Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay | Homo sapiens | 10 | ALA4411315 | cell-based format | Scientific Literature | |
18. | ALA4413552 | Functional | Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay | Homo sapiens | 10 | ALA4411315 | cell-based format | Scientific Literature | |
19. | ALA4413553 | Functional | Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay | Homo sapiens | 10 | ALA4411315 | cell-based format | Scientific Literature | |
20. | ALA4413554 | Binding | Inhibition of recombinant human full length N-terminal His-tagged/untagged p110alpha/p85alpha expressed in baculovirus expression system at 1000 nM using PIP2 as substrate after 1 hr by Kinase-Glo reagent-based assay relative to control | Homo sapiens | 3 | ALA4411315 | assay format | Scientific Literature |