# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4405142 | Binding | Inhibition of human PI3Kalpha assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex at 1 uM using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay relative to control | Homo sapiens | 10 | ALA4402587 | single protein format | Scientific Literature | |
2. | ALA4405143 | Binding | Inhibition of human PI3Kbeta assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex at 1 uM using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay relative to control | Homo sapiens | 10 | ALA4402587 | single protein format | Scientific Literature | |
3. | ALA4405144 | Binding | Inhibition of human PI3Kgamma assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex at 1 uM using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay relative to control | Homo sapiens | 10 | ALA4402587 | single protein format | Scientific Literature | |
4. | ALA4405145 | Binding | Inhibition of human PI3Kdelta assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex at 1 uM using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay relative to control | Homo sapiens | 10 | ALA4402587 | single protein format | Scientific Literature | |
5. | ALA4405146 | Binding | Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in baculovirus infected Sf21 insect cells at 10 uM using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay relative to control | Homo sapiens | 10 | ALA4402587 | cell-based format | Scientific Literature | |
6. | ALA4405147 | Binding | Inhibition of recombinant human GST-tagged HDAC2 (1 to 488 residues) expressed in baculovirus infected sf21 cells at 10 uM using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay relative to control | Homo sapiens | 10 | ALA4402587 | cell-based format | Scientific Literature | |
7. | ALA4405148 | Binding | Inhibition of recombinant full length human C-terminal His-tagged HDAC3 (1 to 428 residues) expressed in baculovirus infected insect cells at 10 uM using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay relative to control | Homo sapiens | 10 | ALA4402587 | cell-based format | Scientific Literature | |
8. | ALA4405149 | Binding | Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1125 residues) expressed in baculovirus infected insect cells at 10 uM using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay relative to control | Homo sapiens | 10 | ALA4402587 | cell-based format | Scientific Literature | |
9. | ALA4405150 | Binding | Inhibition of recombinant C-terminal His-fusion tagged and N-terminal Streptavidin2-tagged human HDAC8 (1 to 377 residues) expressed in insect cells at 10 uM using fluorogenic peptide p53 residues 379-382 (RHK(Ac)K(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay relative to control | Homo sapiens | 10 | ALA4402587 | cell-based format | Scientific Literature | |
10. | ALA4405151 | Binding | Inhibition of HDAC10 (unknown origin) at 10 uM using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay relative to control | Homo sapiens | 10 | ALA4402587 | single protein format | Scientific Literature |