# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4401997 | Binding | Inhibition of rat neuronal NOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Rattus norvegicus | 21 | ALA4400558 | assay format | Scientific Literature | |
2. | ALA4401998 | Binding | Inhibition of human neuronal NOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Homo sapiens | 21 | ALA4400558 | assay format | Scientific Literature | |
3. | ALA4401999 | Binding | Selectivity ratio of Ki for human neuronal NOS to Ki for rat neuronal NOS | 21 | ALA4400558 | assay format | Scientific Literature | ||
4. | ALA4402000 | ADME | Effective permeability of the compound at 200 uM after 17 hrs by PAMPA-BBB assay | 21 | ALA4400558 | assay format | Scientific Literature | ||
5. | ALA4402001 | ADME | Apparent permeability from apical to basolateral side in human Caco2 cells at 5 uM after 90 mins | Homo sapiens | 6 | ALA4400558 | cell-based format | Scientific Literature | |
6. | ALA4402002 | ADME | Apparent permeability from basolateral to apical side in human Caco2 cells at 5 uM after 90 mins | Homo sapiens | 6 | ALA4400558 | cell-based format | Scientific Literature | |
7. | ALA4402003 | ADME | Efflux ratio of apparent permeability in human Caco2 cells at 5 uM after 90 mins | Homo sapiens | 6 | ALA4400558 | cell-based format | Scientific Literature | |
8. | ALA4402004 | ADME | Inhibition of human endothelial NOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Homo sapiens | 7 | ALA4400558 | assay format | Scientific Literature | |
9. | ALA4402005 | ADME | Inhibition of human iNOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Homo sapiens | 7 | ALA4400558 | assay format | Scientific Literature | |
10. | ALA4402006 | ADME | Inhibition of mouse iNOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Mus musculus | 7 | ALA4400558 | assay format | Scientific Literature | |
11. | ALA4402007 | Binding | Selectivity ratio of Ki for human endothelial NOS to Ki of human neuronal NOS | Homo sapiens | 7 | ALA4400558 | assay format | Scientific Literature | |
12. | ALA4402008 | Binding | Selectivity ratio of Ki for human iNOS to Ki of human neuronal NOS | Homo sapiens | 7 | ALA4400558 | assay format | Scientific Literature | |
13. | ALA4402009 | Binding | Selectivity ratio of Ki for rat endothelial NOS to Ki of mouse iNOS | Rattus norvegicus | 7 | ALA4400558 | assay format | Scientific Literature |