| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4385196 | B | Inhibition of calf thymus topoisomerase-1 assessed as reduction in cleavage complex formation by measuring decrease in nicked form DNA using supercoiled pBR322 DNA as substrate after 30 mins by agarose gel electrophoresis assay | Bos taurus | 1 | single protein format | Scientific Literature | ||
| 2. | ALA4385197 | B | Inhibition of calf thymus topoisomerase-1 assessed as reduction in cleavage complex formation by measuring nicked form DNA level using supercoiled pBR322 DNA as substrate after 30 mins by agarose gel electrophoresis assay (Rvb = 47%) | Bos taurus | 3 | single protein format | Scientific Literature | ||
| 3. | ALA4385198 | B | Inhibition of supercoiled pBR322 DNA binding to calf thymus topoisomerase-1 after 0.5 hrs by agarose gel electrophoresis assay | Bos taurus | 2 | single protein format | Scientific Literature | ||
| 4. | ALA4385199 | B | Inhibition of calf thymus topoisomerase-1-mediated supercoiled pBR322 DNA unwinding at 25 uM preincubated with DNA for 10 mins followed by enzyme addition and measured after 30 mins by agarose gel electrophoresis assay | Bos taurus | 3 | single protein format | Scientific Literature | ||
| 5. | ALA4385200 | B | Inhibition of calf thymus topoisomerase-1-mediated relaxed pBR322 DNA unwinding at 25 uM preincubated with DNA for 10 mins followed by enzyme addition and measured after 30 mins by agarose gel electrophoresis assay | Bos taurus | 3 | single protein format | Scientific Literature |
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