# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4339112 | B | Inhibition of human N-terminal GST-tagged IDO1 expressed in Escherichia coli Rosetta(DE3) pLysS using L-tryptophan as substrate measured after 1 hr by fluorescence assay | Homo sapiens | 26 | assay format | Scientific Literature | ||
2. | ALA4339113 | B | Inhibition of IDO1 in interferon-gamma-induced human SKOV3 cells assessed as N-formylkynurenine formation using L-tryptophan as substrate measured after 24 hrs by fluorescence assay | Homo sapiens | 26 | assay format | Scientific Literature | ||
3. | ALA4339114 | A | Half life in human liver microsomes | Homo sapiens | 20 | microsome format | Scientific Literature | ||
4. | ALA4339115 | A | Half life in mouse liver microsomes | Mus musculus | 20 | microsome format | Scientific Literature | ||
5. | ALA4339116 | A | Stability assessed as recombinant UGT1A9 (unknown origin) mediated compound glucuronidation by measuring half-life at 1 uM incubated in water bath by shaking at 37 degree C measured upto 60 mins in presence of UDPGA by LC-MS/MS analysis | Homo sapiens | 23 | single protein format | Scientific Literature |