| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4429195 | B | Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 15 | ALA4428062 | cell-based format | Scientific Literature | |
| 2. | ALA4429196 | B | Agonist activity at human TLR2 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
| 3. | ALA4429197 | B | Agonist activity at human TLR3 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
| 4. | ALA4429198 | B | Agonist activity at human TLR4 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
| 5. | ALA4429199 | B | Agonist activity at human TLR5 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
| 6. | ALA4429200 | B | Agonist activity at human TLR7 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
| 7. | ALA4429201 | B | Agonist activity at human TLR9 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene assay | Homo sapiens | 7 | ALA4428062 | cell-based format | Scientific Literature | |
| 8. | ALA4429202 | B | Agonist activity at TLR8 in human PBMC assessed as increase in TNF-alpha production after 16 hrs by immunoassay | Homo sapiens | 5 | ALA4428062 | single protein format | Scientific Literature | |
| 9. | ALA4429203 | B | Agonist activity at TLR8 in human PBMC assessed as Th1-biased stimulatory activity measured as IFNgamma release after 16 hrs by immunoassay | Homo sapiens | 4 | ALA4428062 | single protein format | Scientific Literature | |
| 10. | ALA4429204 | B | Agonist activity at TLR8 in human PBMC assessed as Th1-biased stimulatory activity measured as IL-12 release after 16 hrs by immunoassay | Homo sapiens | 4 | ALA4428062 | single protein format | Scientific Literature | |
| 11. | ALA4429205 | B | Agonist activity at TLR8 in human PBMC assessed as induction of IL-1beta levels after 16 hrs by immunoassay | Homo sapiens | 5 | ALA4428062 | single protein format | Scientific Literature | |
| 12. | ALA4429206 | B | Agonist activity at TLR8 in human PBMC assessed as induction of IL-6 levels after 16 hrs by immunoassay | Homo sapiens | 5 | ALA4428062 | single protein format | Scientific Literature | |
| 13. | ALA4429207 | B | Agonist activity at TLR8 in human PBMC assessed as induction of IL-8 levels after 16 hrs by immunoassay | Homo sapiens | 5 | ALA4428062 | single protein format | Scientific Literature | |
| 14. | ALA4429208 | B | Agonist activity at TLR8 in human monocytes assessed as upregulation of CD80 after 16 hrs by flow cytometry | Homo sapiens | 3 | ALA4428062 | cell-based format | Scientific Literature |
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