# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4428883 | Binding | Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assay | Homo sapiens | 37 | ALA4428053 | cell-based format | Scientific Literature | |
2. | ALA4428884 | Binding | Inhibition of human Nav1.5 expressed in HEK293 cells incubated for 3 to 5 mins at -50 mV holding potential by electrophysiology assay | Homo sapiens | 37 | ALA4428053 | cell-based format | Scientific Literature | |
3. | ALA4428886 | ADME | Intrinsic clearance in human liver microsomes at 1 uM after 1 to 40 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 30 | ALA4428053 | microsome format | Scientific Literature | |
4. | ALA4428887 | ADME | Intrinsic clearance in rat liver microsomes at 1 uM after 1 to 40 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 30 | ALA4428053 | microsome format | Scientific Literature |