# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4434176 | B | Inhibition of recombinant GST-tagged human full length CDK14/cyclin Y (2 to end residues) preincubated for 30 mins by Lantha screen eu binding assay | Homo sapiens | 100 | protein complex format | Scientific Literature | ||
2. | ALA4434177 | F | Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by cell titer glo-based luminescence assay | Homo sapiens | 100 | cell-based format | Scientific Literature | ||
3. | ALA4434178 | B | Inhibition of FLAG-tagged CDK14 (unknown origin) expressed in human HEK293 cells assessed as blocking of CDK14 pulldown incubated for 4 hrs by biotinylated JNK-IN- based pull down assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
4. | ALA4434179 | B | Covalent binding affinity to GST-tagged human full length CDK14/cyclin Y (2 to end residues) assessed as formation of covalent bond formation at 10:1 M ratio of compound to CDK14/Cyclin Y protein incubated for 3 hrs by MS/MS analysis | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
5. | ALA4434180 | B | Inhibition of CDK16 in human HCT116 cells at 1 uM incubated for 4 hrs by KINATIV live cell profiling protocol based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA4434186 | B | Inhibition of FLAG-tagged CDK14 (unknown origin) expressed in human HEK293 cells assessed as blocking of CDK14 pulldown at 500 to 1000 nM incubated for 4 hrs by biotinylated JNK-IN- based pull down assay | Homo sapiens | 3 | cell-based format | Scientific Literature |