# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4386804 | Functional | Positive allosteric modulation of human M4 AchR expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization | Homo sapiens | 40 | ALA4385625 | cell-based format | Scientific Literature | |
2. | ALA4386805 | Functional | Positive allosteric modulation of human M4 AchR expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization relative to acetylcholine alone | Homo sapiens | 40 | ALA4385625 | cell-based format | Scientific Literature | |
3. | ALA4386807 | ADME | Plasma clearance in rat | Rattus norvegicus | 4 | ALA4385625 | assay format | Scientific Literature | |
4. | ALA4386814 | ADME | Unbound brain-to-plasma concentration ratio in rat | Rattus norvegicus | 4 | ALA4385625 | cell-free format | Scientific Literature | |
5. | ALA4386817 | Binding | Positive allosteric modulation of human M2 AchR | Homo sapiens | 4 | ALA4385625 | single protein format | Scientific Literature |