# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4316880 | ADME | Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay | Homo sapiens | 31 | ALA4316587 | cell-based format | Scientific Literature | |
2. | ALA4316881 | Functional | Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay | Homo sapiens | 31 | ALA4316587 | cell-based format | Scientific Literature | |
3. | ALA4316882 | Functional | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 31 | ALA4316587 | cell-based format | Scientific Literature | |
4. | ALA4316883 | Functional | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay | Homo sapiens | 31 | ALA4316587 | cell-based format | Scientific Literature | |
5. | ALA4316884 | Functional | Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay | Homo sapiens | 31 | ALA4316587 | cell-based format | Scientific Literature | |
6. | ALA4316885 | Functional | Antiproliferative activity against human T24 cells after 48 hrs by MTT assay | Homo sapiens | 31 | ALA4316587 | cell-based format | Scientific Literature | |
7. | ALA4316886 | ADME | Antiproliferative activity against human HL7702 cells after 48 hrs by MTT assay | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature | |
8. | ALA4316887 | Binding | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as DNA intercalation at 50 uM after 1 hr by ethidium bromide staining-based agarose gel electrophoresis analysis | Escherichia coli | 14 | ALA4316587 | nucleic acid format | Scientific Literature | |
9. | ALA4316888 | Binding | Inhibition of topoisomerase 1 (unknown origin) at 50 uM using pBR322 DNA as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by ethidium bromide staining-based agarose gel electrophoresis analysis | Homo sapiens | 14 | ALA4316587 | single protein format | Scientific Literature | |
10. | ALA4316889 | Binding | Inhibition of topoisomerase 1 (unknown origin) at 40 uM using pBR322 DNA as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by ethidium bromide staining-based agarose gel electrophoresis analysis | Homo sapiens | 1 | ALA4316587 | single protein format | Scientific Literature | |
11. | ALA4316890 | Binding | Inhibition of topoisomerase 1 (unknown origin) using pBR322 DNA as substrate assessed as reduction in pBR322 DNA unwinding at 50 uM after 30 mins by ethidium bromide staining-based agarose gel electrophoresis analysis | Homo sapiens | 14 | ALA4316587 | single protein format | Scientific Literature | |
12. | ALA4316891 | Binding | Inhibition of topoisomerase 1 (unknown origin) using pBR322 DNA as substrate assessed as reduction in pBR322 DNA unwinding at 20 uM after 30 mins by ethidium bromide staining-based agarose gel electrophoresis analysis | Homo sapiens | 1 | ALA4316587 | single protein format | Scientific Literature | |
13. | ALA4316892 | Functional | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at G1 phase at 1 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 54.37%) | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature | |
14. | ALA4316893 | Functional | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at G2 phase at 1 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 3.77%) | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature | |
15. | ALA4316894 | Functional | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at S phase at 1 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 41.88%) | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature | |
16. | ALA4316895 | Functional | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at G1 phase at 2 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 54.37%) | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature | |
17. | ALA4316896 | Functional | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at G2 phase at 2 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 3.77%) | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature | |
18. | ALA4316897 | Functional | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at S phase at 2 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 41.88%) | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature | |
19. | ALA4316898 | Functional | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at G1 phase at 8 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 54.37%) | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature | |
20. | ALA4316899 | Functional | Cell cycle arrest in human MGC803 cells assessed as accumulation of cells at G2 phase at 8 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 3.77%) | Homo sapiens | 1 | ALA4316587 | cell-based format | Scientific Literature |