# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4372581 | B | Binding affinity to tRNA cytosine methyl transferase in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
2. | ALA4372588 | B | Inhibition of deubiquitinase in HEK293T cells expressing N-terminal HA-tagged ubiquitin assessed as stabilization of HMW-Ub proteins after 2 hrs by Western blot analysis | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
3. | ALA4372619 | B | Inhibition of recombinant His6-tagged USP7 catalytic domain (unknown origin) assessed as association constant using Ub-AMC as substrate by fluorescence assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
4. | ALA4372620 | B | Inhibition of recombinant His6-tagged USP9x catalytic domain (unknown origin) assessed as association constant using Ub-AMC as substrate by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
5. | ALA4372621 | B | Inhibition of papaya papain at 100 uM using Z-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Carica papaya | 5 | single protein format | Scientific Literature | ||
6. | ALA4372622 | B | Inhibition of fig ficin at 100 uM using Z-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Carica papaya | 5 | assay format | Scientific Literature | ||
7. | ALA4372623 | B | Inhibition of recombinant His6-tagged SENP6 catalytic domain (628 to 1112 residues) (unknown origin) at 1 to 25 uM using SUMO2-modified RanGap1 as substrate preincubated for 30 mins followed by substrate addition and measured after 10 mins by Western blot analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
8. | ALA4372624 | B | Inhibition of porcine pancreatic elastase | Sus scrofa | 2 | protein format | Scientific Literature | ||
9. | ALA4372625 | A | Substrate activity at chymotrypsin (unknown origin) by Michaelis-Menten plot analysis | Homo sapiens | 2 | protein format | Scientific Literature | ||
10. | ALA4372626 | A | Substrate activity at trypsin (unknown origin) by Michaelis-Menten plot analysis | Homo sapiens | 2 | protein format | Scientific Literature | ||
11. | ALA4372627 | B | Binding affinity to OTUB1 in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
12. | ALA4372628 | B | Binding affinity to IMPDH2 in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
13. | ALA4372629 | B | Binding affinity to CASP7 in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
14. | ALA4372630 | B | Binding affinity to thioredoxin in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
15. | ALA4372631 | B | Binding affinity to GAPDH in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
16. | ALA4372632 | B | Binding affinity to peroxiredoxin in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
17. | ALA4372633 | B | Binding affinity to E3 ligase in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
18. | ALA4372634 | B | Binding affinity to GST-omega in human HeLa cell lysates assessed as cysteine-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
19. | ALA4372635 | B | Binding affinity to D-3-phosphoglycerate dehydrogenase in human HeLa cell lysates assessed as C369-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
20. | ALA4372636 | B | Binding affinity to MCM6 in human HeLa cell lysates assessed as C101-compound adduct formation at 50 uM preincubated for 22 mins followed by IAA-probe addition and measured after 20 mins by mass spectrometric method | Homo sapiens | 1 | subcellular format | Scientific Literature |