# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4481214 | B | Displacement of [125I] RTI-55 from recombinant human full length NET expressed in MDCK cells at 10 uM after 120 mins by scintillation counting relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA4481215 | B | Displacement of [3H]DAMGO from recombinant human mu-type opioid receptor at 10 uM after 120 mins by scintillation counting relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA4481216 | A | Drug degradation in rat liver microsomes at 1 uM measured over 60 mins by LC-MS/MS analysis | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
4. | ALA4481217 | A | Drug degradation in human liver microsomes at 1 uM measured over 60 mins by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
5. | ALA4481218 | A | Degradation half life in rat liver microsomes at 1 uM by LC-MS/MS analysis | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
6. | ALA4481219 | A | Degradation half life in human liver microsomes at 1 uM by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
7. | ALA4481220 | A | Drug degradation in rat plasma at 1000 ng/ml measured over 240 mins by LC-MS/MS analysis | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
8. | ALA4481221 | A | Degradation half life in rat plasma at 1000 ng/ml by LC-MS/MS analysis | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
9. | ALA4481222 | A | Drug degradation in human plasma at 1000 ng/ml measured over 240 mins by LC-MS/MS analysis | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
10. | ALA4481223 | A | Degradation half life in human plasma at 1000 ng/ml by LC-MS/MS analysis | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
11. | ALA4481224 | B | Displacement of [3H]RX821002 from recombinant human alpha2A adrenoceptor at 10 uM after 60 mins by scintillation counting relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA4481229 | B | Inhibition of recombinant human GlyT1b expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp electrophysiology | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
13. | ALA4481230 | B | Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp electrophysiology | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
14. | ALA4481231 | B | Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp electrophysiology relative to control | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
15. | ALA4481232 | B | Agonist activity at MOR in mouse AtT-20 cells assessed as increase in IGIRK currents at 1 uM in presence of -60 mV holding potential measured every 2 secs by patch clamp assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
16. | ALA4481233 | B | Antagonist activity at MOR in mouse AtT-20 cells assessed as inhibition of agonist-induced IGIRK currents at 1 uM in presence of -60 mV holding potential measured every 2 secs by patch clamp assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
17. | ALA4481234 | B | Agonist activity at human SPR1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA4481235 | B | Antagonist activity at human SPR1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA4481236 | B | Agonist activity at human CB1 receptor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA4481237 | B | Antagonist activity at human CB1 receptor | Homo sapiens | 1 | single protein format | Scientific Literature |