| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4314078 | F | Antiproliferative activity against human Bel7402 incubated for 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 2. | ALA4314079 | F | Antiproliferative activity against human Bel7402/5-FU incubated for 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 3. | ALA4314080 | A | Cytotoxicity against mouse 3T3 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4314081 | T | Therapeutic index, ratio of IC50 for mouse 3T3 cells to IC50 for human Bel7402 cells | 1 | assay format | Scientific Literature | |||
| 5. | ALA4314082 | T | Therapeutic index, ratio of IC50 for mouse 3T3 cells to IC50 for human Bel7402/5-FU cells | 1 | assay format | Scientific Literature | |||
| 6. | ALA4314085 | F | Down regulation of MDR1 expression in human Bel7402/5-FU cells incubated for 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4314086 | F | Down regulation of ABCC1 expression in human Bel7402/5-FU cells incubated for 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4314087 | F | Down regulation of ABCG2 expression in human Bel7402/5-FU cells incubated for 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4314088 | F | Down regulation of Pgp expression in human Bel7402/5-FU cells at 0.5 uM incubated for 30 by flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4314089 | F | Induction of apoptosis in human Bel7402/5-FU cells assessed as upregulation of Bax expression at 0.5 to 5 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4314090 | F | Increase in ADR intracellular accumulation in human Bel7402/5-FU cells preincubated for 24 hrs followed by adriamycin addition measured after 4 hrs by flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4314091 | F | Induction of apoptosis in human Bel7402/5-FU assessed as apoptotic cells at 0.5 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 3.37 +/- 0.47 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4314092 | F | Induction of apoptosis in human Bel7402/5-FU assessed as apoptotic cells at 1 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 3.37 +/- 0.47 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4314093 | F | Induction of apoptosis in human Bel7402/5-FU assessed as apoptotic cells at 2.5 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 3.37 +/- 0.47 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4314094 | F | Induction of apoptosis in human Bel7402/5-FU assessed as apoptotic cells at 5 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 3.37 +/- 0.47 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4314095 | F | Induction of apoptosis in human Bel7402/5-FU assessed as necrotic cells at 1 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 0.024 to 0.157 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4314096 | F | Induction of apoptosis in human Bel7402/5-FU assessed as early apoptotic cells at 1 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 20.1 to 20.3 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4314097 | F | Induction of apoptosis in human Bel7402/5-FU assessed as late apoptotic cells at 1 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 0.268 to 0.945 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4314098 | F | Induction of apoptosis in human Bel7402/5-FU assessed as viable cells at 1 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 96.9 to 97.1 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4314099 | F | Induction of apoptosis in human Bel7402/5-FU assessed as necrotic cells at 2.5 uM incubated for 24 hrs by annexinV-FITC/propidium iodide staining based flow cytometry (Rvb = 0.024 to 0.157 %) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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