# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4478056 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins in presence of sodium-free HEPES buffer by liquid scintillation counting | Homo sapiens | 2 | ALA4477203 | cell-based format | Scientific Literature | |
2. | ALA4478058 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as apparent association rate constant after 2 to 180 mins by liquid scintillation counting | Homo sapiens | 2 | ALA4477203 | cell-based format | Scientific Literature | |
3. | ALA4478062 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as time required for complete association by liquid scintillation counting | Homo sapiens | 2 | ALA4477203 | cell-based format | Scientific Literature | |
4. | ALA4478063 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as unspecific binding in presence of N'-[(2S)-2-[[(2S)-5-[[N'-(4-aminobutylcarbamoyl)carbamimidoyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]octanediamide by liquid scintillation counting | Homo sapiens | 1 | ALA4477203 | cell-based format | Scientific Literature | |
5. | ALA4478064 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as fast dissociation rate constant preincubated for 2 hrs followed by addition of N'-[(2S)-2-[[(2S)-5-[[N'-(4-aminobutylcarbamoyl)carbamimidoyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]octanediamide by liquid scintillation counting | Homo sapiens | 1 | ALA4477203 | cell-based format | Scientific Literature | |
6. | ALA4478065 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as slow dissociation rate constant preincubated for 2 hrs followed by addition of N'-[(2S)-2-[[(2S)-5-[[N'-(4-aminobutylcarbamoyl)carbamimidoyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]octanediamide by liquid scintillation counting | Homo sapiens | 1 | ALA4477203 | cell-based format | Scientific Literature | |
7. | ALA4478072 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as fast dissociation half life t1/2(1) at 1.5 uM incubated for 2 hrs in presence of 200-fold excess of N'-[(2S)-2-[[(2S)-5-[[N'-(4-aminobutylcarbamoyl)carbamimidoyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]octanediamide by liquid scintillation counting | Homo sapiens | 1 | ALA4477203 | cell-based format | Scientific Literature | |
8. | ALA4478073 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as slow dissociation half life t1/2(2) at 1.5 uM incubated for 2 hrs in presence of 200-fold excess of N'-[(2S)-2-[[(2S)-5-[[N'-(4-aminobutylcarbamoyl)carbamimidoyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]octanediamide by liquid scintillation counting | Homo sapiens | 1 | ALA4477203 | cell-based format | Scientific Literature | |
9. | ALA4478074 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as slow dissociation constant at 1.5 uM incubated for 2 hrs in presence of 200-fold excess of N'-[(2S)-2-[[(2S)-5-[[N'-(4-aminobutylcarbamoyl)carbamimidoyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]octanediamide by liquid scintillation counting | Homo sapiens | 1 | ALA4477203 | cell-based format | Scientific Literature | |
10. | ALA4478075 | B | Binding affinity to human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ assessed as slow dissociation half life at 1.5 uM incubated for 2 hrs in presence of 200-fold excess of N'-[(2S)-2-[[(2S)-5-[[N'-(4-aminobutylcarbamoyl)carbamimidoyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-pentanoyl]amino]-4-methyl-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]octanediamide by liquid scintillation counting | Homo sapiens | 1 | ALA4477203 | cell-based format | Scientific Literature |