# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4350367 | Binding | Inhibition of CDK7/cyclin H (unknown origin) assessed as residual activity in presence of ATP at Km concentration by radiometric assay | Homo sapiens | 5 | ALA4346756 | protein complex format | Scientific Literature | |
2. | ALA4350368 | Binding | Inhibition of human C-terminal His6-tagged full length CDK6/N-terminal GST-tagged cyclin D3 assessed as residual activity in presence of ATP at Km concentration by radiometric assay | Homo sapiens | 5 | ALA4346756 | protein complex format | Scientific Literature | |
3. | ALA4350369 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) assessed as residual activity in presence of ATP at Km concentration by radiometric assay | Homo sapiens | 5 | ALA4346756 | protein complex format | Scientific Literature | |
4. | ALA4350370 | Binding | Inhibition of human C-terminal His6-tagged full length CDK2/N-terminal GST-tagged cyclin A assessed as residual activity in presence of ATP at Km concentration by radiometric assay | Homo sapiens | 5 | ALA4346756 | protein complex format | Scientific Literature | |
5. | ALA4350371 | Binding | Inhibition of human C-terminal His6-tagged full length CDK1/N-terminal GST-tagged cyclinB assessed as residual activity in presence of ATP at Km concentration by radiometric assay | Homo sapiens | 5 | ALA4346756 | protein complex format | Scientific Literature | |
6. | ALA4350372 | Binding | Selectivity ratio of Ki for recombinant His-tagged MNK2 (unknown origin) to Ki for recombinant GST-tagged MNK1 (unknown origin) by ADP-Glo assay | Homo sapiens | 3 | ALA4346756 | assay format | Scientific Literature | |
7. | ALA4350374 | Binding | Inhibition of recombinant His-tagged MNK2 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at Km concentration by ADP-Glo assay | Homo sapiens | 6 | ALA4346756 | single protein format | Scientific Literature | |
8. | ALA4350375 | Binding | Inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at km concentration by ADP-Glo assay | Homo sapiens | 6 | ALA4346756 | single protein format | Scientific Literature | |
9. | ALA4350376 | Binding | Inhibition of recombinant GST-tagged MNK1 (unknown origin) assessed as residual activity at 10 uM by IMAP TR-FRET assay relative to control | Homo sapiens | 24 | ALA4346756 | single protein format | Scientific Literature | |
10. | ALA4350377 | Binding | Inhibition of recombinant His-tagged MNK2 (unknown origin) assessed as residual activity at 10 uM by IMAP TR-FRET assay relative to control | Homo sapiens | 24 | ALA4346756 | single protein format | Scientific Literature | |
11. | ALA4350378 | Binding | Inhibition of human C-terminal 6His-tagged full-length CDK9/cyclin T1 assessed as residual activity in presence of ATP at Km concentration by radiometric assay | Homo sapiens | 5 | ALA4346756 | protein complex format | Scientific Literature | |
12. | ALA5137653 | Binding | Binding affinity to Mnk1 (unknown origin) | Homo sapiens | 7 | ALA5136973 | single protein format | Scientific Literature | |
13. | ALA5137654 | Binding | Binding affinity to Mnk2 (unknown origin) | Homo sapiens | 7 | ALA5136973 | single protein format | Scientific Literature |