# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4400282 | Binding | Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assay | Homo sapiens | 15 | ALA4396961 | cell-based format | Scientific Literature | |
2. | ALA4400283 | Binding | Inhibition of murine soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence based assay | Mus musculus | 15 | ALA4396961 | cell-based format | Scientific Literature | |
3. | ALA4400284 | ADME | Microsomal stability in human microsomes assessed as parent compound remaining in presence of NADP, glucose-6-phosphate and glucose-6-phosphate dehydrogenase measured after 60 mins by UPLC-MS/MS analysis | Homo sapiens | 15 | ALA4396961 | microsome format | Scientific Literature | |
4. | ALA4400285 | Physicochemical | Solubility of compound in 1% DMSO : 99% PBS buffer solution at 37 degree C measured after 2 hrs by nephelometer analysis | 14 | ALA4396961 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4400286 | ADME | Apparent permeability across apical to basolateral membrane in human Caco2 cells at 10 uM measured after 2 hrs by UPLC-MS/MS analysis | Homo sapiens | 8 | ALA4396961 | cell-based format | Scientific Literature | |
6. | ALA4400287 | ADME | Apparent permeability across basolateral to apical membrane in human Caco2 cells at 10 uM measured after 2 hrs by UPLC-MS/MS analysis | Homo sapiens | 8 | ALA4396961 | cell-based format | Scientific Literature | |
7. | ALA4400288 | ADME | Efflux ratio of apparent permeability across basolateral to apical membrane over apical to basolateral membrane in human Caco2 cells at 10 uM measured after 2 hrs by UPLC-MS/MS analysis | Homo sapiens | 8 | ALA4396961 | cell-based format | Scientific Literature |