# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4393559 | Functional | Antiallergic activity in DNP-HSA-stimulated rat RBL2H3 cells assessed as inhibition of anti-DNP-IgE-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 20 mins followed by DNP-BSA stimulation | Rattus norvegicus | 3 | ALA4392874 | cell-based format | Scientific Literature | |
2. | ALA4393560 | Functional | Antiallergic activity in rat RBL2H3 cells assessed as inhibition of A23187-induced beta hexosaminidase release after 1 hr by para-nitrophenyl-N-acetyl-beta-d-glucosaminide substrate based assay | Rattus norvegicus | 3 | ALA4392874 | cell-based format | Scientific Literature | |
3. | ALA4393561 | Functional | Antiallergic activity in rat RBL2H3 cells assessed as inhibition of A23187/PMA-induced beta hexosaminidase release after 1 hr by para-nitrophenyl-N-acetyl-beta-d-glucosaminide substrate based assay | Rattus norvegicus | 3 | ALA4392874 | cell-based format | Scientific Literature | |
4. | ALA4393562 | ADME | Cytotoxicity against rat RBL2H3 cells assessed as reduction in cell viability at 6.3 to 50 ug/ml measured after 3 hrs by CCK8 assay | Rattus norvegicus | 3 | ALA4392874 | cell-based format | Scientific Literature | |
5. | ALA4393563 | ADME | Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 12.5 to 100 ug/ml measured after 12 hrs by crystal violet staining based assay | Homo sapiens | 5 | ALA4392874 | cell-based format | Scientific Literature |