| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4412490 | B | Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system using fluorescence-labeled substrate by off-chip mobility shift assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 2. | ALA4412494 | B | Inhibition of TAK1 (unknown origin) at 1 uM by LanthaScreen Eu kinase binding assay relative to control | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 3. | ALA4412495 | B | Inhibition of TAK1 (unknown origin) at 0.1 uM by LanthaScreen Eu kinase binding assay relative to control | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 4. | ALA4412497 | F | Growth inhibition of human SW620 cells after 96 hrs by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4412501 | A | Stability in human liver microsomes assessed as parent compound remaining after 60 mins in presence of NADPH by HPLC analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 6. | ALA4412502 | A | Stability in mouse liver microsomes assessed as parent compound remaining after 60 mins in presence of NADPH by HPLC analysis | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 7. | ALA4412503 | A | Stability in human plasma assessed as parent compound remaining after 6 hrs by LC-MS/MS analysis | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 8. | ALA4412504 | A | Stability in mouse plasma assessed as parent compound remaining after 6 hrs by LC-MS/MS analysis | Mus musculus | 2 | cell-free format | Scientific Literature | ||
| 9. | ALA4412509 | A | AUC (0 to 7 hrs) in ICR mouse at 10 mg/kg, po administered as single dose or 3 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4412510 | A | Cmax in ICR mouse at 10 mg/kg, po administered as single dose or 3 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4412511 | A | Half life in ICR mouse at 10 mg/kg, po administered as single dose or 3 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4412512 | A | Oral bioavailability in ICR mouse at 10 mg/kg administered as single dose by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature |
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