# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4416473 | Binding | Inhibition of recombinant human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in Sf1 cells using PolyGT-Biotin as substrate measured after 3 to 20 hrs by HTRF assay | Homo sapiens | 35 | ALA4414617 | cell-based format | Scientific Literature | |
2. | ALA4416474 | ADME | Inhibition of recombinant human N-terminal His-tagged JAK2 (826 to 1132 residues) expressed in baculovirus expression system using PolyGT-Biotin as substrate measured after 3 to 20 hrs by HTRF assay | Homo sapiens | 35 | ALA4414617 | assay format | Scientific Literature | |
3. | ALA4416475 | Binding | Inhibition of recombinant human GST-tagged JAK1 (866 to 1154 residues) expressed in baculovirus expression system using PolyGT-Biotin as substrate measured after 3 to 20 hrs by HTRF assay | Homo sapiens | 35 | ALA4414617 | assay format | Scientific Literature | |
4. | ALA4416476 | ADME | Cytotoxicity against CHOK1 cells assessed as reduction in ATP levels incubated for 24 hrs by ATPlite luminescence assay | Cricetulus griseus | 24 | ALA4414617 | cell-based format | Scientific Literature |