| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4424780 | B | Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells at 1 uM using H3(1-21)K4(Me3)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 6 | ALA4422684 | cell-based format | Scientific Literature | |
| 2. | ALA4424781 | B | Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(1-21)K4(Me3)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 6 | ALA4422684 | cell-based format | Scientific Literature | |
| 3. | ALA4424782 | B | Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 7 | ALA4422684 | cell-based format | Scientific Literature | |
| 4. | ALA4424783 | B | Potency index, ratio of CPI-455 IC50 to test compound IC50 for human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 2 | ALA4422684 | cell-based format | Scientific Literature | |
| 5. | ALA4424784 | B | Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 6. | ALA4424785 | B | Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 7. | ALA4424786 | B | Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells at 50 uM using H3(21-44)-K36(Me2)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 8. | ALA4424787 | B | Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(21-44)-K36(Me2)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 9. | ALA4424788 | B | Inhibition of human N-terminal FLAG-tagged KDM3A (2 to 1321 residues) expressed in baculovirus infected Sf9 insect cells at 50 uM using H3(1-21)K9(Me1)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 10. | ALA4424789 | B | Inhibition of human N-terminal FLAG-tagged KDM3A (2 to 1321 residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(1-21)K9(Me1)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 11. | ALA4424790 | B | Inhibition of human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli at 50 uM using H3(21-44)-K36(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | assay format | Scientific Literature | |
| 12. | ALA4424791 | B | Inhibition of human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli at 25 uM using H3(21-44)-K36(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | assay format | Scientific Literature | |
| 13. | ALA4424792 | B | Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells at 50 uM using H3(21-44)-K27(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 14. | ALA4424793 | B | Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(21-44)-K27(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 15. | ALA4424794 | B | Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells at 50 uM using H3(1-21)K9(Me2)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 16. | ALA4424795 | B | Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells at 25 uM using H3(1-21)K9(Me2)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay relative to control | Homo sapiens | 4 | ALA4422684 | cell-based format | Scientific Literature | |
| 17. | ALA4424796 | B | Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K36(Me2)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 2 | ALA4422684 | cell-based format | Scientific Literature | |
| 18. | ALA4424798 | B | Inhibition of human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using H3(21-44)-K36(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 1 | ALA4422684 | assay format | Scientific Literature | |
| 19. | ALA4424799 | B | Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K27(Me3)-GK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 3 | ALA4422684 | cell-based format | Scientific Literature | |
| 20. | ALA4424800 | B | Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K9(Me2)-GGK(Biotin)/2-OG as substrate measured after 1 hr by Alphalisa assay | Homo sapiens | 2 | ALA4422684 | cell-based format | Scientific Literature |
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