# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4417505 | Binding | Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669-1210 AA) expressed in baculovirus at 10 uM using FAM-labelled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift assay relative to control | Homo sapiens | 33 | ALA4414679 | assay format | Scientific Literature | |
2. | ALA4417506 | Binding | Inhibition of N-terminal GST-tagged human EGFR (d746-750AA) expressed in baculovirus at 10 uM using FAM-labelled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift assay relative to control | Homo sapiens | 33 | ALA4414679 | assay format | Scientific Literature | |
3. | ALA4417507 | Binding | Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus at 10 uM using FAM-labelled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift assay relative to control | Homo sapiens | 33 | ALA4414679 | assay format | Scientific Literature | |
4. | ALA4417508 | Binding | Inhibition of N-terminal GST-tagged human FGFR1 cytoplasmic domain (398-822 AA) expressed in baculovirus at 10 uM using FAM-labelled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift assay relative to control | Homo sapiens | 33 | ALA4414679 | assay format | Scientific Literature | |
5. | ALA4417509 | Binding | Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669-1210 AA) expressed in baculovirus using FAM-labelled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift assay | Homo sapiens | 4 | ALA4414679 | assay format | Scientific Literature | |
6. | ALA4417510 | Binding | Inhibition of N-terminal GST-tagged human EGFR (d746-750AA) expressed in baculovirus using FAM-labelled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift assay | Homo sapiens | 4 | ALA4414679 | assay format | Scientific Literature | |
7. | ALA4417511 | Binding | Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus using FAM-labelled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift assay | Homo sapiens | 4 | ALA4414679 | assay format | Scientific Literature | |
8. | ALA4417512 | Binding | Inhibition of N-terminal GST-tagged human FGFR1 cytoplasmic domain (398-822 AA) expressed in baculovirus using FAM-labelled peptide as substrate pre-incubated for 10 mins followed by substrate addition by mobility shift assay | Homo sapiens | 4 | ALA4414679 | assay format | Scientific Literature | |
9. | ALA4417513 | Functional | Antiproliferative activity against human HCC827 cells assessed as inhibition of cell growth at 10 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 35 | ALA4414679 | cell-based format | Scientific Literature | |
10. | ALA4417514 | Functional | Antiproliferative activity against human PC9 cells assessed as inhibition of cell growth at 10 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 35 | ALA4414679 | cell-based format | Scientific Literature | |
11. | ALA4417515 | Functional | Antiproliferative activity against human NCI-H520 cells assessed as inhibition of cell growth at 10 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 35 | ALA4414679 | cell-based format | Scientific Literature | |
12. | ALA4417516 | Functional | Antiproliferative activity against human NCI-H1581 cells assessed as inhibition of cell growth at 10 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 35 | ALA4414679 | cell-based format | Scientific Literature | |
13. | ALA4417517 | Functional | Antiproliferative activity against human NCI-H226 cells assessed as inhibition of cell growth at 10 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 35 | ALA4414679 | cell-based format | Scientific Literature | |
14. | ALA4417518 | Functional | Antiproliferative activity against human HCC827 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4414679 | cell-based format | Scientific Literature | |
15. | ALA4417519 | Functional | Antiproliferative activity against human PC9 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4414679 | cell-based format | Scientific Literature | |
16. | ALA4417520 | Functional | Antiproliferative activity against human NCI-H520 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4414679 | cell-based format | Scientific Literature | |
17. | ALA4417521 | Functional | Antiproliferative activity against human NCI-H1581 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4414679 | cell-based format | Scientific Literature | |
18. | ALA4417522 | Functional | Antiproliferative activity against human NCI-H226 cells incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4414679 | cell-based format | Scientific Literature |