#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4327283	Binding	Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topcount method	Homo sapiens	13	ALA4325862	single protein format	Scientific Literature
2.	ALA4327284	Binding	Inhibition of recombinant human DNMT3a C-terminal catalytic domain (623 to 908 residues) using 5'-biotinylated/3'-FAM-oligonucleotide as substrate measured after 1 hr in presence of Adomet by fluorescence assay	Homo sapiens	11	ALA4325862	single protein format	Scientific Literature
3.	ALA4327285	Binding	Inhibition of recombinant human N-terminal GST-fused G9a (786 to 1210 residues) expressed in Escherichia coli using biotinylated H3 (1 to 21 residues) as substrate measured after 1 hr in presence of 3H-Adomet by filter binding assay	Homo sapiens	13	ALA4325862	assay format	Scientific Literature
4.	ALA4327287	Functional	Antiplasmodial activity against asynchronous form of Plasmodium falciparum 3D7 infected in human erythrocytes assessed as parasite growth inhibition at 10 uM after 48 hrs by SYBR green1 staining based flow cytometry relative to control	Plasmodium falciparum	51	ALA4325862	organism-based format	Scientific Literature
5.	ALA4327288	Functional	Antiplasmodial activity against asynchronous form of Plasmodium falciparum 3D7 infected in human erythrocytes assessed as parasite growth inhibition after 48 hrs by SYBR green1 staining based flow cytometry	Plasmodium falciparum	52	ALA4325862	organism-based format	Scientific Literature
6.	ALA4327289	Functional	Antiplasmodial activity against Plasmodium falciparum Dd2 infected in human erythrocytes assessed as reduction in [3H]-hypoxanthine incorporation measured after 48 hrs by microbeta liquid scintillation counting method	Plasmodium falciparum	8	ALA4325862	organism-based format	Scientific Literature
7.	ALA4327290	Functional	Antiplasmodial activity against asynchronous form of Plasmodium falciparum W2 infected in human erythrocytes assessed as parasite growth inhibition after 48 hrs by SYBR green1 staining based flow cytometry	Plasmodium falciparum	9	ALA4325862	organism-based format	Scientific Literature
8.	ALA4327291	ADME	Cytotoxicity against mouse spleen cells	Mus musculus	8	ALA4325862	cell-based format	Scientific Literature
9.	ALA4327292	Toxicity	Selectivity index, ratio of IC50 for asynchronous form of Plasmodium falciparum 3D7 infected in human erythrocytes to IC50 for mouse spleen cells		8	ALA4325862	cell-based format	Scientific Literature
10.	ALA4327293	ADME	Cytotoxicity against HFF	Homo sapiens	8	ALA4325862	cell-based format	Scientific Literature
11.	ALA4327294	Toxicity	Selectivity index, ratio of IC50 for asynchronous form of Plasmodium falciparum 3D7 infected in human erythrocytes to IC50 for HFF		8	ALA4325862	cell-based format	Scientific Literature
12.	ALA4327295	Physicochemical	Stability in phosphate buffered saline at pH 7.4 after 24 hrs by UV/RP-HPLC analysis		3	ALA4325862	small-molecule physicochemical format	Scientific Literature
13.	ALA4327303	ADME	Plasma concentration in Crl:NRMI mouse at 50 mg/kg, po administered via gavage measured after 30 mins by LC-MS/MS analysis	Mus musculus	3	ALA4325862	organism-based format	Scientific Literature
14.	ALA4327304	ADME	Plasma concentration in Crl:NRMI mouse at 50 mg/kg, po administered via gavage measured after 60 mins by LC-MS/MS analysis	Mus musculus	3	ALA4325862	organism-based format	Scientific Literature
15.	ALA4327305	ADME	Plasma concentration in Crl:NRMI mouse at 50 mg/kg, po administered via gavage measured after 180 mins by LC-MS/MS analysis	Mus musculus	3	ALA4325862	organism-based format	Scientific Literature
16.	ALA4327309	Toxicity	Acute toxicity in Crl:NRMI mouse assessed as death at 50 mg/kg, iv measured after 15 to 180 mins by LC-MS/MS analysis	Mus musculus	2	ALA4325862	organism-based format	Scientific Literature
17.	ALA4327311	Functional	Antimalarial activity against Plasmodium berghei ANKA infected in BALB/c mouse assessed as reduction in parasitemia at 50 mg/kg, po administered twice daily for 4 days by Giemsa-staining based microscopic analysis	Plasmodium berghei	2	ALA4325862	organism-based format	Scientific Literature
18.	ALA4327320	Functional	Antimalarial activity against Plasmodium berghei ANKA infected in BALB/c mouse assessed as parasitemia at 50 mg/kg, po administered twice daily for 4 days measured up to 14 days post infection by Giemsa-staining based microscopic analysis (Rvb = 31 to 58%)	Plasmodium berghei	1	ALA4325862	organism-based format	Scientific Literature