# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4308417 | Binding | Inhibition of PDE4B in human PBMC assessed as inhibition in LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation for 18 hrs by TR-FRET analysis | Homo sapiens | 17 | ALA4304825 | single protein format | Scientific Literature | |
2. | ALA4308423 | Binding | Inhibition of PDE4B in human U937 cells using [3H] cAMP as substrate incubated for 30 mins | Homo sapiens | 17 | ALA4304825 | cell-based format | Scientific Literature | |
3. | ALA4308424 | ADME | Inhibition of PDE4D in human U937 cells using [3H]cAMP as substrate incubated for 30 mins | Homo sapiens | 17 | ALA4304825 | cell-based format | Scientific Literature |