# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4409447 | Functional | Antiproliferative activity against human KARPAS299 cells expressing NMP-ALK assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 26 | ALA4406858 | cell-based format | Scientific Literature | |
2. | ALA4409448 | Functional | Antiproliferative activity against human SH-SY5Y cells expressing ALK F1174L mutant assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 8 | ALA4406858 | cell-based format | Scientific Literature | |
3. | ALA4409449 | Functional | Antiproliferative activity against human SK-N-BE(2) cells expressing wild type ALK assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 8 | ALA4406858 | cell-based format | Scientific Literature | |
4. | ALA4409450 | Functional | Antiproliferative activity against human NCI-H2228 cells expressing EML4-ALK assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 8 | ALA4406858 | cell-based format | Scientific Literature | |
5. | ALA4409451 | Binding | Inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) expressed in baculovirus expression system using Srctide as substrate incubated with enzyme and substrate for 5 mins followed by ATP addition followed by further incubation for 30 mins by HTRF assay | Homo sapiens | 6 | ALA4406858 | assay format | Scientific Literature | |
6. | ALA4409452 | Binding | Inhibition of recombinant human N-terminal GST-tagged ALK L1196M mutant (1058 to 1620 residues) expressed in baculovirus expression system using Srctide as substrate incubated with enzyme and substrate for 5 mins followed by ATP addition followed by further incubation for 30 mins by HTRF assay | Homo sapiens | 6 | ALA4406858 | assay format | Scientific Literature |