| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4308758 | B | Inhibition of His-tagged/GST-tagged LCK (unknown origin) incubated for 1 hr by TR-FRET assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 2. | ALA4308759 | B | Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 3. | ALA4308760 | B | Effect on ZAP70 phosphorylation in human Jurkat cells pre-incubated for 30 mins followed by anti-CD3/CD28 stimulation measured after 10 mins | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA4308761 | B | Effect on ZAP70 phosphorylation in human Jurkat cells pre-incubated for 30 mins followed by anti-CD3/CD28 stimulation measured after 10 mins relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4308762 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 0.5 uM measured after 10 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 14 | microsome format | Scientific Literature | ||
| 6. | ALA4308763 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining at 0.5 uM measured after 10 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 14 | microsome format | Scientific Literature | ||
| 7. | ALA4308764 | B | Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper method | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 8. | ALA4308765 | A | Half life in human liver microsomes at 0.5 uM measured up to 45 mins by LC-MS/MS analysis | Homo sapiens | 4 | microsome format | Scientific Literature | ||
| 9. | ALA4308766 | A | Half life in mouse liver microsomes at 0.5 uM measured up to 45 mins by LC-MS/MS analysis | Mus musculus | 4 | microsome format | Scientific Literature | ||
| 10. | ALA4308767 | A | Protein binding in human serum assessed as unbound fraction measured up to 5 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
| 11. | ALA4308768 | A | Protein binding in mouse serum assessed as unbound fraction measured up to 5 hrs by LC-MS/MS analysis relative to control | Mus musculus | 4 | cell-free format | Scientific Literature |
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