#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4404824	Binding	Inhibition of JAK1-JH1/JH2 domain (574 to 1154 residues) (unknown origin) pre-incubated before NH2-KGGEEEEYFELVKK-CO2 substrate addition and measured after 90 mins by MS analysis	Homo sapiens	12	ALA4402578	single protein format	Scientific Literature
2.	ALA4404825	Binding	Inhibition of JAK2-JH1/JH2 domain (532 to 1132 residues) (unknown origin) pre-incubated before NH2-KGGEEEEYFELVKK-CO2 substrate addition and measured after 90 mins by MS analysis	Homo sapiens	12	ALA4402578	single protein format	Scientific Literature
3.	ALA4404826	Binding	Inhibition of JAK3-JH1/JH2 domain (512 to 1124 residues) (unknown origin) pre-incubated before NH2-KGGEEEEYFELVKK-CO2 substrate addition and measured after 45 mins by MS analysis	Homo sapiens	12	ALA4402578	single protein format	Scientific Literature
4.	ALA4404827	Binding	Inhibition of Tyk2 -JH1/JH2 domain (532 to 1132 residues) 8H_tev_580-1182-C936A-C1142A mutant (unknown origin) pre-incubated before NH2-KGGEEEEYFELVKK-CO2 substrate addition and measured after 90 mins by MS analysis	Homo sapiens	12	ALA4402578	assay format	Scientific Literature
5.	ALA4404828	Binding	Inhibition of JAK1/JAK3 in human PBMC assessed as reduction in IL2-induced STAT5 phosphorylation pre-incubated for 30 mins before IL2 stimulation for 30 mins AlphaLISAassay	Homo sapiens	12	ALA4402578	protein complex format	Scientific Literature
6.	ALA4404829	Binding	Inhibition of JAK2/JAK2 in human PBMC assessed as reduction in GM-CSF-induced STAT5 phosphorylation pre-incubated for 30 mins before GM-CSF stimulation for 30 mins AlphaLISAassay	Homo sapiens	12	ALA4402578	single protein format	Scientific Literature
7.	ALA4404830	Binding	Inhibition of JAK1/Tyk2 in human PBMC assessed as reduction in IFNalpha-induced STAT4 phosphorylation pre-incubated for 30 mins before IFNalpha stimulation for 30 mins AlphaLISAassay	Homo sapiens	12	ALA4402578	protein complex format	Scientific Literature
8.	ALA4404831	ADME	Permeability from apical to basolateral side in MDCK-MDR1 cells at 5 uM by LC/MS/MS analysis	Canis lupus familiaris	12	ALA4402578	cell-based format	Scientific Literature
9.	ALA4404833	ADME	Hepatic extraction ratio in mouse liver microsomes at 1 uM in presence of NADPH incubated up to 60 mins by LC/MS/MS analysis	Mus musculus	12	ALA4402578	microsome format	Scientific Literature
10.	ALA4404834	ADME	Plasma concentration in C57BL/6 mouse at 25 mg/kg, po measured after 0.5 hrs by LC-MS/MS analysis	Mus musculus	12	ALA4402578	organism-based format	Scientific Literature
11.	ALA4404835	ADME	Plasma concentration in C57BL/6 mouse at 25 mg/kg, po measured after 4 hrs by LC-MS/MS analysis	Mus musculus	12	ALA4402578	organism-based format	Scientific Literature
12.	ALA4404836	ADME	Drug concentration in C57BL/6 mouse colon at 25 mg/kg, po measured after 4 hrs by LC-MS/MS analysis	Mus musculus	12	ALA4402578	organism-based format	Scientific Literature