# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4431262 | Binding | Inhibition of human recombinant JAK1 using Ulight-CAGAGAIETDKEYYTVKD as substrate at 20 nM by LANCE assay relative to control | Homo sapiens | 24 | ALA4428138 | single protein format | Scientific Literature | |
2. | ALA4431263 | Binding | Inhibition of human recombinant JAK2 using Ulight-CAGAGAIETDKEYYTVKD as substrate at 20 nM by LANCE assay relative to control | Homo sapiens | 24 | ALA4428138 | single protein format | Scientific Literature | |
3. | ALA4431264 | Binding | Inhibition of human recombinant JAK3 using Ulight-CAGAGAIETDKEYYTVKD as substrate at 20 nM by LANCE assay relative to control | Homo sapiens | 24 | ALA4428138 | single protein format | Scientific Literature | |
4. | ALA4431268 | Functional | Antiproliferative activity against HEL cells harboring JAK2 V617F mutant at 5 uM after 48 hrs by MTT assay | Homo sapiens | 23 | ALA4428138 | cell-based format | Scientific Literature | |
5. | ALA4431269 | Functional | Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay | Homo sapiens | 11 | ALA4428138 | cell-based format | Scientific Literature | |
6. | ALA4431270 | Functional | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 11 | ALA4428138 | cell-based format | Scientific Literature | |
7. | ALA4431271 | Functional | Antiproliferative activity against HEL cells harboring JAK2 V617F mutant after 48 hrs by MTT assay | Homo sapiens | 11 | ALA4428138 | cell-based format | Scientific Literature | |
8. | ALA4431272 | Functional | Antiproliferative activity against human K562 cells after 48 hrs by MTT assay | Homo sapiens | 11 | ALA4428138 | cell-based format | Scientific Literature | |
9. | ALA4431273 | Functional | Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay | Homo sapiens | 11 | ALA4428138 | cell-based format | Scientific Literature |