| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4429211 | B | Agonist activity at human TLR7 expressed in HEK293 cells measured after 6 hrs by NF-kappaB luciferase reporter gene assay | Homo sapiens | 36 | ALA4428063 | cell-based format | Scientific Literature | |
| 2. | ALA4429212 | B | Agonist activity at human TLR8 expressed in HEK293 cells assessed as measured after 6 hrs by NF-kappaB luciferase reporter gene assay | Homo sapiens | 36 | ALA4428063 | cell-based format | Scientific Literature | |
| 3. | ALA4429213 | A | Cytotoxicity against HEK293 cells measured after 6 hrs | Homo sapiens | 33 | ALA4428063 | cell-based format | Scientific Literature | |
| 4. | ALA4429214 | A | Apparent permeability across apical to basolateral side in MDCK cells expressing human MDR1 at 1 uM in presence of GF120918 by LC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 5. | ALA4429215 | A | Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in MDCK cells expressing human MDR1 at 1 uM by LC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 6. | ALA4429216 | B | Agonist activity at wild-type human TLR1 expressed in HEK293 cells up to 25 uM measured after 6 hrs by NF-kappaB luciferase reporter gene assay | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 7. | ALA4429217 | B | Agonist activity at wild-type human TLR9 expressed in HEK293 cells up to 25 uM measured after 6 hrs by NF-kappaB luciferase reporter gene assay | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 8. | ALA4429218 | A | Cytotoxicity against human HepG2 cells measured after 72 hrs by multiplex end point analysis | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 9. | ALA4429219 | F | Induction of IFN-alpha production in human PBMC | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 10. | ALA4429220 | F | Induction of IFN-gamma production in human PBMC | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 11. | ALA4429221 | F | Induction of IL-12p40 production in human PBMC | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 12. | ALA4429222 | F | Induction of IL-12p70 production in human PBMC | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 13. | ALA4429223 | F | Induction of TNF-alpha production in human PBMC | Homo sapiens | 1 | ALA4428063 | cell-based format | Scientific Literature | |
| 14. | ALA4429224 | A | Fraction absorbed in Sprague-Dawley rat plasma at 10 mg/kg, po | Rattus norvegicus | 1 | ALA4428063 | organism-based format | Scientific Literature | |
| 15. | ALA4429225 | A | Tmax in Sprague-Dawley rat plasma at 10 mg/kg, po | Rattus norvegicus | 1 | ALA4428063 | organism-based format | Scientific Literature | |
| 16. | ALA4429226 | A | Tmax in Sprague-Dawley rat liver at 10 mg/kg, po | Rattus norvegicus | 1 | ALA4428063 | organism-based format | Scientific Literature | |
| 17. | ALA4429227 | A | Cmax in Sprague-Dawley rat plasma at 10 mg/kg, po | Rattus norvegicus | 1 | ALA4428063 | organism-based format | Scientific Literature | |
| 18. | ALA4429228 | A | Cmax in Sprague-Dawley rat liver at 10 mg/kg, po | Rattus norvegicus | 1 | ALA4428063 | organism-based format | Scientific Literature | |
| 19. | ALA4429229 | A | Ratio of drug level in Sprague-Dawley rat liver to plasma at 10 mg/kg, po | Rattus norvegicus | 1 | ALA4428063 | organism-based format | Scientific Literature | |
| 20. | ALA4429230 | A | Hepatic extraction ratio in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | ALA4428063 | organism-based format | Scientific Literature |
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