# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4342180 | B | Induction of p53 phosphorylation at S392, S46, S15 residues in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
2. | ALA4342181 | F | Antiproliferative activity against human K562 cells assessed as inhibition of cell viability incubated for 72 hrs by real time live-cell imaging technique | Homo sapiens | 11 | ALA4340560 | cell-based format | Scientific Literature | |
3. | ALA4342182 | F | Induction of apoptosis in human K562 cells assessed as increase in apoptotic cells at 10 uM incubated for 24 to 48 hrs by Caspase-3/7 reagent-based fluorescence assay | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
4. | ALA4342184 | B | Inhibition of AKT1/2/3 phosphorylation (S473/T308 residues) in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
5. | ALA4342185 | B | Inhibition of PI3K/Akt signaling in human K562 cells assessed as reduction in p70S6K phosphorylation at T421/S424 residues up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
6. | ALA4342186 | B | Inhibition of PI3K/Akt signaling in human K562 cells assessed as reduction in mTOR phosphorylation at S2448 residues up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
7. | ALA4342187 | B | Inhibition of PI3K/Akt signaling in human K562 cells assessed as reduction in GSK3alpha/beta phosphorylation at S21/S9 residues up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
8. | ALA4342188 | B | Inhibition of PYK2 phosphorylation in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
9. | ALA4342189 | B | Induction of p27 phosphorylation at T198 residues in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
10. | ALA4342190 | B | Inhibition of MAPK signalling in human K562 cells assessed as effect on p38 phosphorylation up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
11. | ALA4342191 | B | Inhibition of RAF/MEK/ERK signalling n human K562 cells assessed as reduction in ERK1/2 phosphorylation at T202/Y204, T185/Y187 residues up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
12. | ALA4342192 | B | Inhibition of SRC phosphorylation in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
13. | ALA4342193 | B | Inhibition of LCK phosphorylation in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
14. | ALA4342194 | B | Inhibition of RAF/MEK/ERK signalling n human K562 cells assessed as reduction in RSK1/2/3 phosphorylation at S380/S386/S377 residues up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
15. | ALA4342195 | B | Inhibition of MAPK signalling in human K562 cells assessed as effect on HSP27 phosphorylation up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
16. | ALA4342196 | B | Inhibition of MAPK signalling in human K562 cells assessed as effect on JNK phosphorylation up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
17. | ALA4342197 | B | Inhibition of WNK1 phosphorylation at T60 residue in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
18. | ALA4342198 | B | Inhibition of PRAS40 phosphorylation at T246 residue in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature | |
19. | ALA4342199 | B | Inhibition of STAT signalling in human K562 cells up to 10 uM incubated for 48 hrs by human phospho-kinase array | Homo sapiens | 1 | ALA4340560 | cell-based format | Scientific Literature |