| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4374264 | Functional | Antiviral activity against Respiratory syncytial virus Long infected in HEp-2 cells assessed as reduction in virus induced cytopathic effect measured after 6 days by MTT assay | Respiratory syncytial virus | 26 | ALA4373654 | organism-based format | Scientific Literature | |
| 2. | ALA4374265 | ADME | Cytotoxicity against human Hep2 cells assessed as reduction in cell viability after 6 days by MTT assay | Homo sapiens | 26 | ALA4373654 | cell-based format | Scientific Literature | |
| 3. | ALA4374266 | Toxicity | Therapeutic index, ratio of CC50 for cytotoxicity against human Hep2 cells to EC50 for antiviral activity against Respiratory syncytial virus Long infected in HEp-2 cells | 26 | ALA4373654 | cell-based format | Scientific Literature | ||
| 4. | ALA4374267 | ADME | Clearance in mouse liver microsomes | Mus musculus | 4 | ALA4373654 | microsome format | Scientific Literature | |
| 5. | ALA4374268 | Physicochemical | Solubility of compound by LYSA assay | 4 | ALA4373654 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4374277 | ADME | AUC in ICR mouse at 25 mg/kg, po administered as single dose | Mus musculus | 3 | ALA4373654 | organism-based format | Scientific Literature | |
| 7. | ALA4374278 | ADME | Clearance in ICR mouse at 5 mg/kg, iv or 25 mg/kg, po administered as single dose | Mus musculus | 3 | ALA4373654 | organism-based format | Scientific Literature | |
| 8. | ALA4374279 | ADME | Volume of distribution at steady state in ICR mouse at 5 mg/kg, iv administered as single dose | Mus musculus | 3 | ALA4373654 | organism-based format | Scientific Literature | |
| 9. | ALA4374280 | ADME | Half life in ICR mouse at 25 mg/kg, po administered as single dose | Mus musculus | 3 | ALA4373654 | organism-based format | Scientific Literature |
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