# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4410949 | B | Inhibition of human recombinant GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 peptide as substrate incubated for 1 hr by LanthaScreen assay | Homo sapiens | 19 | assay format | Scientific Literature | ||
2. | ALA4410950 | B | Inhibition of mTORC1 in human A431 cells assessed as S6RP phosphorylation incubated for 3 hrs by HTRF assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
3. | ALA4410951 | B | Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
4. | ALA4410952 | B | Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by TR-FRET assay | Homo sapiens | 19 | single protein format | Scientific Literature | ||
5. | ALA4410953 | P | Kinetic aqueous solubility of compound in phosphate buffer at pH 7.4 at 100 uM at 20 degree C shaken for 24 hrs by HPLC analysis | 19 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA4410954 | P | Lipophilicity, chromatographic hydrophobicity index of compound at 0.5 mM at pH 6.5 by UPLC-UV analysis | 19 | small-molecule physicochemical format | Scientific Literature |