# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4406959 | Functional | Anti-necroptotic activity in human HT-29 cells assessed as inhibition of NFalpha/SM-164/Z-VAD-fmk-induced necroptosis measured after 12 hrs by celltiter-glo luminescent cell viability assay | Homo sapiens | 37 | ALA4406794 | cell-based format | Scientific Literature | |
2. | ALA4406960 | ADME | Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system after 1 hr by quantitative PCR based KINOMEscan assay | Homo sapiens | 28 | ALA4406794 | assay format | Scientific Literature | |
3. | ALA4406961 | Binding | Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system after 1 hr by quantitative PCR based KINOMEscan assay | Homo sapiens | 28 | ALA4406794 | assay format | Scientific Literature | |
4. | ALA4406963 | ADME | Cytotoxicity against human HT-29 cells measured after 12 hrs by CellTiter-Glo Luminescent assay | Homo sapiens | 28 | ALA4406794 | cell-based format | Scientific Literature |