# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4382905 | Binding | Inhibition of human N-terminal His6-tagged GGPPS expressed in Escherichia coli BL21(DE3) using [14C]-IPP and FPP as substrates after 10 mins by scintillation counting | Homo sapiens | 13 | ALA4382196 | assay format | Scientific Literature | |
2. | ALA4382906 | Binding | Inhibition of human FPPS using [14C]-IPP and FPP as substrates after 10 mins by scintillation counting | Homo sapiens | 13 | ALA4382196 | single protein format | Scientific Literature | |
3. | ALA4382911 | Functional | Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4382196 | cell-based format | Scientific Literature | |
4. | ALA4382912 | Binding | Inhibition of human N-terminal His6-tagged GGPPS Y246D mutant expressed in Escherichia coli BL21(DE3) using [14C]-IPP and FPP as substrates after 10 mins by scintillation counting | Homo sapiens | 14 | ALA4382196 | assay format | Scientific Literature | |
5. | ALA4382935 | Functional | Antiproliferative activity against human NCI-ADR-RES cells after 72 hrs by celltiter-glo luminescent assay | Homo sapiens | 2 | ALA4382196 | cell-based format | Scientific Literature | |
6. | ALA4382936 | Functional | Antiproliferative activity against human MIAPaCa2 cells at 10 uM after 72 hrs by celltiter-glo luminescent assay | Homo sapiens | 2 | ALA4382196 | cell-based format | Scientific Literature | |
7. | ALA4382957 | Functional | Antiproliferative activity against human HT1080 cells at 10 uM after 72 hrs by celltiter-glo luminescent assay | Homo sapiens | 1 | ALA4382196 | cell-based format | Scientific Literature | |
8. | ALA4382958 | Functional | Antiproliferative activity against human HT-29 cells at 10 uM after 72 hrs by celltiter-glo luminescent assay | Homo sapiens | 1 | ALA4382196 | cell-based format | Scientific Literature | |
9. | ALA4382959 | Functional | Antiproliferative activity against human HCT116 cells at 10 uM after 72 hrs by celltiter-glo luminescent assay | Homo sapiens | 1 | ALA4382196 | cell-based format | Scientific Literature | |
10. | ALA4382960 | Functional | Antiproliferative activity against human T98G cells at 10 uM after 72 hrs by celltiter-glo luminescent assay | Homo sapiens | 1 | ALA4382196 | cell-based format | Scientific Literature | |
11. | ALA4382961 | Functional | Antiproliferative activity against human A549 cells at 10 uM after 72 hrs by celltiter-glo luminescent assay | Homo sapiens | 1 | ALA4382196 | cell-based format | Scientific Literature | |
12. | ALA5048364 | Functional | Antiproliferative activity against human RPMI-8226 cells assessed as reduction in cell proliferation after 72 hrs by MTS assay | Homo sapiens | 27 | ALA5046266 | cell-based format | Scientific Literature |