# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4311537 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as minimum concentration required to effectively reduce ciprofloxacin MIC by four fold by broth checkerboard microdilution method | Staphylococcus aureus | 18 | single protein format | Scientific Literature | ||
2. | ALA4311539 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as reduction in ethidium bromide efflux at 50 uM measured over 5 mins interval for 30 mins by fluorescence assay relative to control | Staphylococcus aureus | 5 | single protein format | Scientific Literature | ||
3. | ALA4311540 | F | Potentiation of ciprofloxacin-induced antibacterial activity in Staphylococcus aureus 1199 assessed as reduction in ciprofloxacin MIC at 0.8 to 50 ug/ml by broth checkerboard microdilution method relative to control | Staphylococcus aureus | 18 | organism-based format | Scientific Literature | ||
4. | ALA4311541 | F | Potentiation of ciprofloxacin-induced antibacterial activity in norA-deleted Staphylococcus aureus K1758 assessed as reduction in ciprofloxacin MIC at 0.8 to 50 ug/ml by broth checkerboard microdilution method relative to control | Staphylococcus aureus | 18 | organism-based format | Scientific Literature | ||
5. | ALA4311542 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as assessed as potentiation of ciprofloxacin-induced antibacterial activity by measuring reduction in ciprofloxacin MIC at 25 to 50 ug/ml by broth checkerboard microdilution method relative to control | Staphylococcus aureus | 2 | single protein format | Scientific Literature | ||
6. | ALA4311544 | A | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability at 100 uM after 24 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4311546 | B | Inhibition of NorA Staphylococcus aureus 1199B assessed as reduction in ethidium bromide efflux at 6.25 to 50 uM measured at 5 mins interval for 30 mins by fluorescence assay relative to control | Staphylococcus aureus | 3 | single protein format | Scientific Literature | ||
8. | ALA4311547 | A | Growth inhibition of Staphylococcus aureus 1199 at 50 ug/ml by broth microdilution method | Staphylococcus aureus | 18 | organism-based format | Scientific Literature | ||
9. | ALA4311548 | A | Growth inhibition of norA-deleted Staphylococcus aureus K1758 at 50 ug/ml by broth microdilution method | Staphylococcus aureus | 18 | organism-based format | Scientific Literature | ||
10. | ALA4311549 | B | Inhibition of NorA in Staphylococcus aureus 1199B assessed as reduction in ethidium bromide accumulation at 25 uM measured at 5 mins interval for 60 mins by fluorescence assay relative to control | Staphylococcus aureus | 4 | single protein format | Scientific Literature |