| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4370511 | Functional | Antifungal activity against Cryptococcus neoformans var. grubii H99 after 48 hrs by serial dilution method | Cryptococcus neoformans | 22 | ALA4368921 | organism-based format | Scientific Literature | |
| 2. | ALA4370512 | Functional | Antifungal activity against Candida albicans SC5314 after 48 hrs by serial dilution method | Candida albicans | 22 | ALA4368921 | organism-based format | Scientific Literature | |
| 3. | ALA4370513 | Functional | Antifungal activity against Cryptococcus neoformans var. grubii ATCC 34877 after 48 hrs by serial dilution method | Cryptococcus neoformans | 6 | ALA4368921 | organism-based format | Scientific Literature | |
| 4. | ALA4370514 | Functional | Antifungal activity against Cryptococcus gattii ATCC 14116 after 48 hrs by serial dilution method | Cryptococcus gattii | 6 | ALA4368921 | organism-based format | Scientific Literature | |
| 5. | ALA4370515 | Functional | Antibiofilm activity against Cryptococcus neoformans var. grubii H99 at 0.062 ug/mL after 24 hrs by XTT analysis relative to control | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 6. | ALA4370516 | Functional | Antibiofilm activity against Cryptococcus neoformans var. grubii H99 at 0.062 to 8 ug/mL after 24 hrs by XTT analysis | Cryptococcus neoformans | 3 | ALA4368921 | organism-based format | Scientific Literature | |
| 7. | ALA4370517 | Functional | Inhibition of melanin production in Cryptococcus neoformans var. grubii H99 at 16 ug/mL | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 8. | ALA4370518 | Functional | Inhibition of urease production in Cryptococcus neoformans var. grubii H99 at 64 ug/mL | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 9. | ALA4370519 | Functional | Fungistatic activity against Cryptococcus neoformans var. grubii H99 at 0.25 ug/mL up to 48 hrs by time-growth curve assay | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 10. | ALA4370521 | Functional | Fungistatic activity against Cryptococcus neoformans var. grubii H99 up to 48 hrs by time-growth curve assay | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 11. | ALA4370522 | Functional | Fungicidal activity against Cryptococcus neoformans var. grubii H99 at 2 ug/mL after 48 hrs by time-kill assay | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 12. | ALA4370524 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as early apoptotic cells at 0.5 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.05%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 13. | ALA4370525 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as late apoptotic cells at 0.5 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.15%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 14. | ALA4370526 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as necrotic cells at 0.5 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.19%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 15. | ALA4370527 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as early apoptotic cells at 1 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.05%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 16. | ALA4370528 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as late apoptotic cells at 1 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.15%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 17. | ALA4370529 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as necrotic cells at 1 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.19%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 18. | ALA4370530 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as early apoptotic cells at 2 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.05%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 19. | ALA4370531 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as late apoptotic cells at 2 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.15%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature | |
| 20. | ALA4370532 | Functional | Induction of apoptosis in Cryptococcus neoformans var. grubii H99 assessed as necrotic cells at 2 ug/mL after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.19%) | Cryptococcus neoformans | 1 | ALA4368921 | organism-based format | Scientific Literature |
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