# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4362877 | Functional | Antiviral activity against Influenza A virus A/WSN/33 infected in MDCK cells assessed as reduction in virus-induced cytopathic effect at 100 uM after 40 hrs by Celltiter-Glo assay relative to control | Influenza A virus | 6 | ALA4359890 | organism-based format | Scientific Literature | |
2. | ALA4362878 | ADME | Cytotoxicity against dog MDCK cells assessed as cell viability at 100 uM measured after 40 hrs by Celltiter-Glo assay relative to control | Canis lupus familiaris | 3 | ALA4359890 | cell-based format | Scientific Literature | |
3. | ALA4362880 | ADME | Cytotoxicity against dog MDCK cells assessed as reduction in cell viability measured after 40 hrs by Celltiter-Glo assay | Canis lupus familiaris | 5 | ALA4359890 | cell-based format | Scientific Literature | |
4. | ALA4362881 | Binding | Inhibition of influenza A virus A/WSN/33 HA-mediated chicken erythrocytes hemagglutination pretreated with compound followed by erythrocytes addition measured after 30 mins | Influenza A virus | 1 | ALA4359890 | assay format | Scientific Literature | |
5. | ALA4362882 | Functional | Antiviral activity against Influenza A virus A/WSN/33 assessed as inhibition of virus-induced cytopathic effect after 40 hrs by Celltiter-Glo assay | Influenza A virus | 5 | ALA4359890 | organism-based format | Scientific Literature | |
6. | ALA4362883 | Toxicity | Selectivity index, ratio of CC50 for MDCK cells to IC50 for influenza A virus A/WSN/33 | 5 | ALA4359890 | assay format | Scientific Literature | ||
7. | ALA4362884 | Functional | Antiviral activity against Influenza A virus A/Victoria/361/2011(H3N2) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 40 hrs by Celltiter-Glo assay | Influenza A virus | 2 | ALA4359890 | organism-based format | Scientific Literature | |
8. | ALA4362885 | Functional | Antiviral activity against Influenza B virus B/Yamagata/16/88(BY) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 40 hrs by Celltiter-Glo assay | Influenza B virus | 2 | ALA4359890 | organism-based format | Scientific Literature | |
9. | ALA4362886 | Functional | Antiviral activity against Influenza B virus B/Sichuan/531/2018(BV) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 40 hrs by Celltiter-Glo assay | Influenza B virus | 2 | ALA4359890 | organism-based format | Scientific Literature | |
10. | ALA4362887 | Functional | Antiviral activity against Influenza B virus B/Massachusetts/2/2012(BV) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 40 hrs by Celltiter-Glo assay | Influenza B virus | 2 | ALA4359890 | organism-based format | Scientific Literature | |
11. | ALA4362888 | Functional | Potency index, ratio of OSV-p IC50 to compound IC50 for antiviral activity against Influenza B virus B/Yamagata/16/88(BY) | Influenza B virus | 1 | ALA4359890 | organism-based format | Scientific Literature | |
12. | ALA4362889 | ADME | Cytotoxicity against dog MDCK cells assessed as reduction in cell viability at 100 uM measured after 40 hrs by Celltiter-Glo assay | Canis lupus familiaris | 20 | ALA4359890 | cell-based format | Scientific Literature |